Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Bioinformation Analysis Reveals IFIT1 as Potential Biomarkers in Central Nervous System Tuberculosis
Wenbin Qiao,1,* Jiahui Fan,1,* Xiaoqian Shang,1,* Liang Wang,2 Bahetibieke Tuohetaerbaike,2 Ying Li,2 Li Zhang,2 YiShan Huo,1 Jing Wang,3 Xiumin Ma1,2 1State Key Laboratory of Pathogenesis, Prevention and Treatment of High Incidence Diseases ...
Qiao W +9 more
doaj
Central nervous system tuberculosis reactivation following intravenous iron supplementation
Patients with inflammatory bowel disease (IBD) are often treated with tumor necrosis factor (TNF)-alpha inhibitors and are therefore at higher risk for tuberculosis (TB) reactivation.
Stamatis Karakonstantis +3 more
doaj +1 more source
Nanoparticle delivery through the BBB in central nervous system tuberculosis
Recent advances in Nanotechnology have revolutionized the production of materials for biomedical applications. Nowadays, there is a plethora of nanomaterials with potential for use towards improvement of human health.
Anna Griego +3 more
doaj +1 more source
Mortality associated with central nervous system tuberculosis [PDF]
Tuberculosis (TB) of the central nervous system (CNSTB) is associated with higher mortality rates than other forms of TB. Epidemiologic associations with and prognostic indicators of CNSTB have not been assessed in a large US population-based study.Between 1995 and 2004 and using a population-based active surveillance study, we compared patients with ...
Hana M, El Sahly +4 more
openaire +2 more sources
Leptomeningitis in a person with radiologically isolated syndrome and latent tuberculosis. A case report with implications for clinical research [PDF]
A 39-year-old man, followed with serial MRI of CNS for a radiologically isolate syndrome (RIS, a recently described condition considered a subclinical form of MS), was hospitalized for the occurrence of a leptomeningitis. Routine blood tests and contrast
Bozzao, Alessandro +8 more
core +1 more source
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner +14 more
wiley +1 more source
A scoring system to effectively evaluate central nervous system tuberculosis in patients with military tuberculosis. [PDF]
There is currently no convenient way to effectively evaluate whether a miliary tuberculosis patient is complicated with central nervous system (CNS) tuberculosis. We aimed to find such a way by analyzing the clinical data of these patients.
Yongjiu Xiao +6 more
doaj +1 more source
The relationship of individual comorbid chronic conditions to diabetes care quality. [PDF]
ObjectiveMultimorbidity affects 26 million persons with diabetes, and care for comorbid chronic conditions may impact diabetes care quality. The aim of this study was to determine which chronic conditions were related to lack of achievement or ...
Bolt, Daniel M +7 more
core +2 more sources
Posterior fossa tuberculosis: Unusual presentations of a common disease and literature review
The burden of tuberculosis is very high in our country and though the number of deaths due to tuberculosis has drastically reduced, still the associated morbidities caused by the disease can be very debilitating.1 Central nervous system tuberculosis is a
Nandita Kujur +2 more
doaj +1 more source

