Indications to hospital admission and isolation of children wish possibile or defined tuberculosis: systematic review and proposed recommendations for pediatric patients leaving in developed countries. [PDF]
, 2015 Tuberculosis (TB) is a re-emerging health problem in developed countries. This paper is part of large guidelines on the global management of TB in children, by a group of scientific societies.
Assante, Lr +10 more
core +2 more sources
A Rare Presentation of Invasive Tuberculosis of the Central Nervous System in an Immunocompetent Patient in a Nonendemic Country. [PDF]
, 2018 We herein report a rare case of a 25-year-old immunocompetent male patient with disseminated tuberculosis of central nervous system (CNS), first presenting as multiple cerebral lesions with no meningeal involvement. Subsequent diagnostic workup disclosed
Campillo, J +3 more
core +1 more source
A Case of Extrapulmonary Tuberculosis Two-Ways [PDF]
, 2019 Tuberculosis (TB) is a widespread epidemic. The World HealthOrganization estimated 10.4 million cases of tuberculosis in 2016,with 490,000 new cases of multi-drug resistant (MDR) TB.1 Theprimary presentation of TB is pulmonary.
Cherabie, Joseph +2 more
core +2 more sources
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018 Tuberculosis meningitis is one of the clinical manifestations of extra-pulmonary TB, which is localized in the central nervous system(CNS). The mortality of these patients is usually caused by the delays in diagnosis and treatment; hence up to this day tuberculosismeningitis remains a health problem.
Silvia Rachmayati +3 more
openaire +2 more sources
Impact of Bacille Calmette-Guerin Vaccination on Neuroradiological Manifestations of Pediatric Tuberculous Meningitis [PDF]
, 2010 The authors conducted this study to identify whether bacille Calmette-Guerin (BCG) vaccination leads to an altered spectrum of neuroimaging findings outcome in pediatric Patients with tuberculous meningitis. This retrospective study was conducted through
Ather M. Taqui +15 more
core +1 more source
Time trend and clinical pattern of extrapulmonary tuberculosis in Serbia, 1993-2007 [PDF]
, 2012 Background/Aim. Increased incidence of extrapulmonary tuberculosis (XPTB) is reported worldwide. Serbia is a country in socio-economic transition period with lowmiddle HIV prevalence and intermediate-to-low tuberculosis (TB) incidence rate, 100 ...
Bulajić Milica V. +2 more
core +1 more source
Standardized Methods for Enhanced Quality and Comparability of Tuberculous Meningitis Studies [PDF]
, 2016 Tuberculous meningitis (TBM) remains a major cause of death and disability in tuberculosis-endemic areas, especially in young children and immunocompromised adults.
Aarnoutse, Robert +18 more
core +1 more source
Infection control in the brain and the eye
Acta Ophthalmologica, EarlyView.Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
Detection of 65 kD heat shock protein in cerebrospinal fluid of tuberculous meningitis patients [PDF]
, 2006 Background Diagnosis of tuberculous meningitis (TBM) is difficult. Rapid confirmatory diagnosis is essential to initiate required therapy. There are very few published reports about the diagnostic significance of 65 kD heat shock protein (hsp) in TBM ...
Anju V Mudaliar +4 more
core +1 more source
High‐Throughput Screening Reveals That CeeNU Acts as a New NLRP3 Inflammasome Inhibitor
MedComm, Volume 7, Issue 5, May 2026.We conducted a high‐throughput screen of 2747 FDA‐approved drugs to identify inhibitors of pyroptosis. We found that CeeNU significantly repressed NLRP3‐dependent IL‐1β release and GSDMD pore‐forming complex. We identified that the arginine 335 amino acid of the NACHT domain of NLRP3 is the critical point for human NLRP3 and CeeNU interaction and ...
Sen‐Lin Ji +11 more
wiley +1 more source