Results 21 to 30 of about 10,396 (184)

Clinical Value of Metagenomic Next‐Generation Sequencing Versus Conventional Methods in Diagnosing Cryptococcal Infection After Kidney Transplantation

Organ Medicine, EarlyView.
This retrospective study evaluated metagenomic next‑generation sequencing (mNGS) against conventional methods (India ink, culture, antigen) for diagnosing cryptococcal infection in 16 kidney transplant recipients. mNGS showed a significantly higher positivity rate (93.8% vs 62.5%, p = 0.031) and shorter turnaround time (24 vs. 120 h, p < 0.001).
Luhao Liu, Rongxin Chen, Haonan Lin, Yuhe Guo, Guanghui Li, Jiali Fang, Zheng Chen   +6 more
wiley   +1 more source

Neuro-meningeal tuberculosis: A pediatric case report and review of the literature

Radiology Case Reports
Pediatric neuro-meningeal tuberculosis leads to high rates of mortality and morbidity. Prompt diagnosis and initiation of treatment are challenging; imaging findings play a key role in establishing the presumptive diagnosis.
Chaimae Lahlou, MD, Chaymae Faraj, MD, Sara Essetti, MD, Ihssan Hadj Hsain, MD, Nazik Allali, PhD, Siham EL Haddad, PhD, Latifa Chat, PhD   +6 more
doaj   +1 more source

Targeting peroxynitrite production in a model of persistent temporomandibular disorder comorbid with migraine

British Journal of Pharmacology, EarlyView.
Background and Purpose The persistence of temporomandibular disorders (TMDs), particularly myogenous, in a person with migraine can lead to exacerbated clinical outcomes and limited response to treatment. The pro‐nociceptive reactive nitroxidative species, peroxynitrite, is involved in migraine mechanisms, but little is known of its role in this ...
Simon Akerman, Ana Belen Salinas‐Abarca, Wei Guo, Daniela Salvemini, Marcela Romero‐Reyes   +4 more
wiley   +1 more source

Efficacy and Safety of Corticosteroids in Tuberculous Meningitis: Systematic Review, Meta‐Analysis, and Meta‐Regression

Brain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Background Tuberculous meningitis (TBM) carries a case fatality rate of up to 50% in resource‐limited settings despite standard anti‐tuberculosis therapy. Adjunctive corticosteroids are widely recommended, yet their effect on mortality and safety across diverse populations remains imprecisely defined.
Ayesha Younas, Rizwana Noor, Muhammad Talha Shaukat, Aisha Ijlal, Irra Tariq, Murtaja Satea, Muhammad Sameer Almas, Rosheen Jamil, Mifrah Rahat Khan Sherwani, Norma Nicole Gamarra Valverde, Maria Qadri, Mahwash Siddiqi, Kashif Qureshi, Kivanc Yangi, Bipin Chaurasia   +14 more
wiley   +1 more source

Mycoplasma bovis involved in pituitary abscess syndrome in a beef heifer concomitantly infected with haemoparasites

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract This case report describes pituitary abscess syndrome (PAS) in a 20‐month‐old Blonde d'Aquitaine heifer with cranial nerve deficits (V, VII, VIII, IX, X and XII) associated with facial hemiparesis, head tilt, ataxia and dysphagia, pneumonia and otitis interna.
Chloé Saada, Manon Gonçalves‐Brandao, Hortensia Robert, Renaud Maillard, Laurent‐Xavier Nouvel   +4 more
wiley   +1 more source

Hydrocephalus Caused by Tuberculous Meningitis in an Immunocompetent Young Adult: A Case Report

International Medical Case Reports Journal, 2023
Rizaldy Taslim Pinzon,1,2 Vanessa Veronica1 1Faculty of Medicine, Duta Wacana Christian University, Yogyakarta, Indonesia; 2Department of Neurology, Bethesda Hospital, Yogyakarta, IndonesiaCorrespondence: Rizaldy Taslim Pinzon, Duta Wacana Christian ...
Pinzon RT, Veronica V
doaj  

Infection control in the brain and the eye

Acta Ophthalmologica, Volume 104, Issue 5, Page e478-e490, August 2026.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Three Different Neurological Manifestations of Tuberculosis – A Case Series

Journal of Association of Pulmonologist of Tamil Nadu
Central nervous system (CNS) – Tuberculosis (TB) is a major public health problem in developing countries such as India. It accounts for 5%–10% of cases of extra pulmonary TB, of which 1% have serious illness.
Dileepan Sureshgraham, Mohanakrishnan Deivasigamani, Balamurugan Santhalingam, Chandrasekar Chokalingam   +3 more
doaj   +1 more source

Cerebral Venous Thrombosis in a Young Adult: Challenges in Diagnosing and Managing Risk Factors in a Resource‐Limited Setting

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Cerebral venous thrombosis should be suspected in young patients with severe headache and seizures, even without clear risk factors. In resource‐limited settings, early imaging and prompt anticoagulation can significantly improve outcomes despite incomplete thrombophilia workup.
Filmon Tesfay, Lidya Mussie, Samuel Tekle, Estifanos Habteab   +3 more
wiley   +1 more source

Multiomics Profiling During Autoimmune Demyelination Highlights a Complex Regulatory Role for Ataxin‐1 in B Cells

Annals of the New York Academy of Sciences, Volume 1561, Issue 1, July 2026.
Ataxin‐1 has been recently implicated in B cell regulation in the context of multiple sclerosis pathology. In this study, we used a multiomics pipeline to profile the B cell transcriptome, epigenome, and proteome in response to encephalitogenic challenges.
Jonathan J. Carver, Rachael R. Denbrock, Kristy M. Lau, Tonya N. Zeczycki, Changhong Yin, Weihua Huang, Alessandro Didonna   +6 more
wiley   +1 more source