Results 21 to 30 of about 470,597 (240)

A case of Clival Tuberculosis and associated meningitis

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2021
Herein we report a 30-year-old man presenting with fevers, headaches and weight loss. On admission he was disorientated and demonstrated no focal signs of neurological deficit. Magnetic resonance imaging revealed a large area of abnormal bone marrow signal centred within the clivus with extension into the sphenoid sinus and signs of associated basal ...
Simon Tiberi, Henry Zhang, Yevedzo Ntuli, William Peter Flynn   +3 more
openaire   +4 more sources

Evaluation of Ceftriaxone Plus Avibactam in an Intracellular Hollow Fiber Model of Tuberculosis: Implications for the Treatment of Disseminated and Meningeal Tuberculosis in Children

The Pediatric Infectious Disease Journal, 2020
Background: Ceftazidime-avibactam is an effective agent for the treatment of tuberculosis (TB) but requires frequent administration because of a short half-life. Due to a longer half-life, ceftriaxone could allow intermittent dosing.
S. Srivastava, J. V. van Zyl, Kayle N Cirrincione, K. Martin, T. Thomas, D. Deshpande, J. Alffenaar, J. Seddon, T. Gumbo   +8 more
semanticscholar   +1 more source

Analysis of influencing factors of dismal prognosis in severe tuberculous meningitis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Objective To investigate the influencing factors related to long ⁃ term prognosis in patients with severe tuberculous meningitis (TBM). Methods One hundred sixty⁃three patients with severe TBM admitted to Tianjin Haihe Hospital from June 2012 to December
LIU Chen⁃chao, LIU Hui⁃quan, YUAN Xiao⁃yong, WANG Jian, CHEN Shen, WANG Yi⁃yi, LIU Xing⁃jun   +6 more
doaj   +1 more source

Intensified antibiotic treatment of tuberculosis meningitis [PDF]

Expert Review of Clinical Pharmacology, 2019
Meningitis is the most severe manifestation of tuberculosis, resulting in death or disability in over 50% of those affected, with even higher morbidity and mortality among patients with HIV or drug resistance. Antimicrobial treatment of Tuberculous meningitis (TBM) is similar to treatment of pulmonary tuberculosis, although some drugs show poor central
Cresswell, F.V., te Brake, L.H., te Brake, L.H., Atherton, R., Ruslami, R., Dooley, Kelly E., Aarnoutse, R.E., van Crevel, R.   +7 more
openaire   +4 more sources

Missed Opportunities in the Diagnosis of Tuberculosis Meningitis

Open Forum Infectious Diseases, 2023
AbstractBackgroundTuberculosis meningitis (TBM) has high mortality and morbidity. Diagnostic delays can impact TBM outcomes. We aimed to estimate the number of potentially missed opportunities (MOs) to diagnose TBM and determine its impact on 90-day mortality.MethodsThis is a retrospective cohort of adult patients with a central nervous system (CNS) TB
Niamh Simmons, Margaret A Olsen, Joanna Buss, Thomas C Bailey, Carlos Mejia-Chew   +4 more
openaire   +3 more sources

Intestinal tuberculosis [PDF]

, 2009
Purpose of reviewIntestinal tuberculosis (TB) is increasing due partly to the HIV pandemic. Its clinical presentation mimics inflammatory conditions such as Crohn's disease and malignancies, which are becoming more prevalent, so the diagnosis is ...
Donoghue, HD, Holton, J
core   +1 more source

Leptomeningitis in a person with radiologically isolated syndrome and latent tuberculosis. A case report with implications for clinical research [PDF]

, 2018
A 39-year-old man, followed with serial MRI of CNS for a radiologically isolate syndrome (RIS, a recently described condition considered a subclinical form of MS), was hospitalized for the occurrence of a leptomeningitis. Routine blood tests and contrast
Bozzao, Alessandro, Chiara Buscarinu, Maria, Ferraldeschi, Michela, Fornasiero, Arianna, Ristori, Giovanni, Romano, Andrea, Romano, Silvia, Salvetti, Marco, Teggi, Antonella   +8 more
core   +1 more source

Resistant Tuberculosis in HIV-Positive Patients: A Growing Public Health Threat

American Journal of Internal Medicine, 2023
: Introduction: Tuberculosis (TB) is a pathology considered one of the main causes of death by single infectious agent, ranking just after HIV / AIDS.
Safae Elfirdaous Fari, Maamar Mouna, Khibri Haja, Nisserine Jait, Y. Moussadik, Thameen Jaradat, Wafae Ammouri, Naima Moutassim, H. Harmouche, Z. Mezalek Tazi, Mohamed Adnoui   +10 more
semanticscholar   +1 more source

Effectiveness of the treatment of generalized tuberculosis in HIV-infected patients

Infusion & Chemotherapy, 2019
. The treatment of tuberculosis in HIV-infected persons is a complex task and often requires intensive therapy with intravenous administration of antituberculosis drugs, especially in generalized forms, malabsorption, presence of enteropathy, hepatitis B
O. D. Nikolaeva
doaj   +1 more source

Immunological diagnosis as an adjunctive tool for an early diagnosis of tuberculous meningitis of an immune competent child in a low tuberculosis endemic country: A case report [PDF]

, 2017
Background: Pediatric tuberculous meningitis is a highly morbid, often fatal disease. Its prompt diagnosis and treat - ment saves lives, in fact delays in the initiation of therapy have been associated with high mortality rates. Case presentation:
Ajassa, Camilla, Caraffa, Emanuela, Ciardi, Rosa Maria, Colistra, Davide, DI BIASI, Claudio, Lichtner, Miriam, Mancarella, Cristina, Mascia, Claudia, Mastroianni, Claudio Maria, Mengoni, Fabio, Paglia, Maria Grazia, Vita, Serena, Vullo, Vincenzo   +12 more
core   +4 more sources