Results 241 to 250 of about 273,523 (312)

Long‐term safety and efficacy of ritlecitinib in adults and adolescents with alopecia areata and at least 25% scalp hair loss: Results from the ALLEGRO‐LT phase 3, open‐label study

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
ALLEGRO‐LT (NCT04006457) is an open‐label, phase 3 study investigating the long‐term safety and efficacy of ritlecitinib in patients with alopecia areata (AA). In this analysis in 449 de novo patients with AA and ≥25% scalp hair loss, ritlecitinib demonstrated clinical efficacy and had an acceptable safety profile through Month 24.
C. Tziotzios   +11 more
wiley   +1 more source

European Guideline (EuroGuiDerm) on atopic eczema: Living update

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
The updated guideline includes a new evidence‐based recommendation for the IL‐13 inhibitor lebrikizumab. In addition, the Janus kinase inhibitors baricitinib and abrocitinib, which were initially only approved for adult patients, are now also recommended for children from the age of 2 and adolescents from the age of 12, respectively.
A. Wollenberg   +31 more
wiley   +1 more source

Infection risk in atopic dermatitis patients treated with biologics and JAK inhibitors: BioDay results

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This cohort study of 1793 atopic dermatitis patients (aged ≥ 12) found higher infection rates with Janus kinase inhibitor treatment compared to biologic treatment, particularly for herpes infections, with a history of viral or fungal skin infection as a risk factor associated with infection.
Lian F. van der Gang   +22 more
wiley   +1 more source

Bilateral Rasmüssen aneurysm in a patient with pulmonary tuberculosis: A case report. [PDF]

open access: yesRadiol Case Rep
Oukrid K   +7 more
europepmc   +1 more source

A comparative analysis of unsupervised machine‐learning methods in PSG‐related phenotyping

open access: yesJournal of Sleep Research, EarlyView.
Summary Obstructive sleep apnea is a heterogeneous sleep disorder with varying phenotypes. Several studies have already performed cluster analyses to discover various obstructive sleep apnea phenotypic clusters. However, the selection of the clustering method might affect the outputs.
Mohammadreza Ghorvei   +9 more
wiley   +1 more source

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