Results 261 to 270 of about 1,739,773 (346)

Deep Vein Thrombosis in Critically Ill Patients With COVID‐19 Pneumonia

open access: yesJournal of Ultrasound in Medicine, Volume 45, Issue 1, Page 155-170, January 2026.
Objectives The risk of major venous thromboembolism (VTE) among patients with COVID‐19 is high but varies with disease severity. Estimate the incidence of lower extremity deep venous thrombosis (DVT) in critically ill hospitalized patients with COVID‐19, validate the Wells score for DVT diagnosis, and determine patients' prognosis.
Clévio Cezar da Fonseca   +20 more
wiley   +1 more source

Robust Diagnostic and Therapeutic Biomarkers for Tuberculosis Identified Through Multi‐Omics and Mendelian Randomization Analysis

open access: yesMedComm, Volume 7, Issue 1, January 2026.
We performed UPLC‐MS/MS lipidomics and DIA proteomics on plasma from healthy controls, active TB patients, and cured patients, and used Mendelian randomization to prioritize diagnostic and cure biomarkers. Multi‐omics random‐forest models based on these biomarkers showed excellent performance for diagnosis and cure monitoring.
Chenglin Zhu   +9 more
wiley   +1 more source

CCR2 Orchestrates Preferential Homing and Therapeutic Efficacy of Gingival Mesenchymal Stem Cell‐Derived Extracellular Vesicles in Rheumatoid Arthritis

open access: yesMedComm, Volume 7, Issue 1, January 2026.
CCR2 orchestrates preferential homing of GMSC‐derived extracellularvesicles to inflamed joints in rheumatoid arthritis. ABSTRACT The clinical utility of mesenchymal stem cells (MSCs) is often limited by pulmonary entrapment and poor systemic distribution, particularly in diseases constrained by physiological barriers such as rheumatoid arthritis (RA ...
Jingrong Chen   +13 more
wiley   +1 more source

Streptococcus pneumoniae HtrA is a dynamic and monomeric virulence factor capable of forming larger oligomeric complexes

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract High‐temperature requirement A (HtrA) proteases are a conserved family of serine proteases central to protein quality control and bacterial virulence. While Gram‐negative and human HtrAs are structurally well studied, Gram‐positive homologs remain essentially uncharacterized.
Eunjeong Lee   +14 more
wiley   +1 more source

Isolated Mediastinal and Hilar Lymphadenopathy as a Manifestation of IgG4‐Related Disease Diagnosed by EBUS‐Guided Transbronchial Mediastinal Cryobiopsy

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
We describe a case of mediastinal and hilar lymphadenopathy diagnosed as IgG4‐RD by transbronchial mediastinal cryobiopsy, fulfilling the 2020 diagnostic criteria, with systemic evaluation confirming no other organ involvement. ABSTRACT Immunoglobulin G4‐related disease (IgG4‐RD) is a fibroinflammatory condition that can involve multiple organs ...
Wen Zhang   +7 more
wiley   +1 more source

A Case of Bronchial Dieulafoy's Disease Presenting as an Endobronchial Polypoid Lesion That Regressed After Bronchial Artery Embolisation

open access: yesRespirology Case Reports, Volume 14, Issue 1, January 2026.
Bronchial Dieulafoy's disease is extremely rare and characterised by a large‐calibre, submucosal artery lying just beneath the mucosa, predisposing to abrupt haemorrhage despite minimal or no mucosal defect. This case highlights the visual confirmation of lesion regression by bronchoscopy after bronchial artery embolisation.
Masayoshi Higashiguchi   +3 more
wiley   +1 more source

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