Results 31 to 40 of about 417,862 (221)

Ocular tuberculosis in a calf.

open access: yesBMC Veterinary Research, 2021
Background Bovine tuberculosis is a chronic inflammatory disease that causes granuloma formation mainly in retropharyngeal, tracheobronchial, mediastinal lymph nodes and lungs of bovines. The presence of these lesions in other tissues such as the eyeball
Jacobo Carrisoza-Urbina   +3 more
doaj   +1 more source

Pharmacophore Modeling and Binding Analysis for targeting Mycobacterium tuberculosis MurC ligase [PDF]

open access: yes, 2010
Despite the availability of effective chemotherapy and the moderately protective vaccine, new anti-Tuberculosis agents are urgently needed to decrease the global incidence of Tuberculosis (TB).
Yogesh N   +3 more
core   +1 more source

Orbital and external ocular manifestations of Mycobacterium tuberculosis: A review of the literature

open access: yesJournal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2016
Tuberculosis (TB) is an airborne infectious disease caused by Mycobacterium tuberculosis that most commonly affects the lungs. However, extrapulmonary manifestations of TB can affect the eye and surrounding orbital tissues.
Lauren A. Dalvin, Wendy M. Smith
doaj   +1 more source

A case report of probable ocular tuberculosis following biologics

open access: yesIndian Journal of Ophthalmology. Case Reports, 2021
Biological drugs, especially anti-TNF-α agents, have revolutionized the treatment of chronic immune-inflammatory diseases, however complications include reactivation of tuberculosis and increased incidence of other infections.
Sudha K. Ganesh, Divya Thatikonda
doaj   +1 more source

Patterns of ocular inflammation in patients with miliary tuberculosis [version 1; referees: 2 approved]

open access: yesF1000Research, 2017
Background: Ocular morbidity associated with systemic tuberculosis is common. The clinical picture varies from anterior uveitis, intermediate uveitis and posterior uveitis to even panuveitis.
Salil Mehta
doaj   +1 more source

Relationship between severity of HIV infection and ocular pathology in patients with pulmonary tuberculosis

open access: yesJournal of Ophthalmology, 2018
Background: Pulmonary tuberculosis most commonly develops and often becomes generalized among HIV-infected patients. HIV-positive individuals present extra-pulmonary forms of tuberculosis twice as often as HIV-negative individuals.
I.N.Voronova   +3 more
doaj   +1 more source

Local ischemia and increased expression of vascular endothelial growth factor following ocular dissemination of Mycobacterium tuberculosis. [PDF]

open access: yesPLoS ONE, 2011
The pathogenesis of intraocular tuberculosis remains poorly understood partly due to the lack of adequate animal models that accurately simulate human disease.
Seema M Thayil   +6 more
doaj   +1 more source

Choroidal granuloma resolution with tuberculosis treatment

open access: yesAmerican Journal of Ophthalmology Case Reports, 2020
Purpose: To report a case of presumed ocular tuberculosis, successfully treated with anti-tubercular therapy alone. Observations: Resolution of a presumed tubercular choroidal granuloma occurred after initiation of 4-drug anti-tubercular therapy, without
LeAnne Young, Mehmet Yakin, H. Nida Sen
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Ocular manifestation of systemic tuberculosis in children at tertiary pediatric hospital in North India

open access: yesKerala Journal of Ophthalmology
Background: Tubnerculosis is Characterised by the presence of granuloma formation. The mode of spread of pulmonary tuberculosis is via airborne aerosol. This bacteria enters the lungs and leads to latent infection in susceptible hosts.
Meenakshi Wadhwani   +3 more
doaj   +1 more source

Home - About - Disclaimer - Privacy