Results 61 to 70 of about 5,402,382 (253)

Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations From the 2015 Strategic Planning Conference [PDF]

, 2016
On March 10 to March 12, 2015, the National Institute of Neurological Disorders and Stroke and the Tuberous Sclerosis Alliance sponsored a workshop in Bethesda, Maryland, to assess progress and new opportunities for research in tuberous sclerosis complex
Darling, Thomas N, Pende, Mario, Thiele, Elizabeth, Ess, Kevin C, Bissler, John J, Nelson, Charles A, Chugani, Diane C, Wu, Joyce Y, Kwiatkowski, David J, Wagner, Andrew J, D'Arcangelo, Gabriella, Murphy, Leon O, Blenis, John, Moss, Joel, Franz, David, Nellist, Mark, St. Hillaire-Clarke, Coryse, de Vries, Petrus J, Klitgaard, Henrik, Klann, Eric, Paul, Elahna, Rosbeck, Kari Luther, Henske, Elizabeth P, Manning, Brendan D, Zervas, Mark, Song, Minkyung H, Weiner, Howard L, Perrimon, Norbert, Sahin, Mustafa, Young, Lisa R, Krueger, Darcy, Northrup, Hope, Crino, Peter B, Wong, Michael, Silva, Alcino J, Cichowski, Karen, Mamounas, Laura A, Long, Cara, Der, Channing, Bebin, E Martina, Gambello, Michael J, Shaw, Reuben J, Rieff, Heather, Roberds, Steven L, Byars, Anna W, Fureman, Brandy E, Macklin, Wendy B, Krymskaya, Vera P, Plan, Tuberous Sclerosis Complex Working Group to Update the Research   +48 more
core   +1 more source

Anodal Transcranial Direct Current Stimulation Improves Social Behavior Alongside Neuroplastic Changes in a Tsc2+/− Rat Model of Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by altered synaptic connectivity and network organization, resulting in profound impairments in social communication and interaction. Transcranial direct current stimulation (tDCS) represents a promising approach to modulate maladaptive plasticity associated with ASD;
Antonia Ramme, Rebecca Winter, Natalia Jarzebska, Fatih Ögel, Marten Julian Richter, Iveta Vojtechova, Christine Winter, Tomas Petrasek, Robert Waltereit, Nadine Bernhardt   +9 more
wiley   +1 more source

Recent advances in the management of lymphangioleiomyomatosis [version 1; referees: 4 approved]

F1000Research, 2018
Lymphangioleiomyomatosis is a rare disorder that predominantly affects women and is characterized by progressive cystic changes in the lung, leading to gradually worsening shortness of breath and lung function impairment.
Kai-Feng Xu, Xinlun Tian, Jay H Ryu
doaj   +1 more source

Localizing value of cutaneous ictal phenomena: A systematic review

Epileptic Disorders, EarlyView.
Abstract Objective Clinical observation of autonomic signs during seizures can aid in localizing the epileptogenic zone (EZ). We performed a systematic review and meta‐analysis to evaluate the localizing value of ictal cutaneous phenomena—piloerection, sweating, pallor, and flushing—in focal epilepsy and their relevance to presurgical evaluation ...
R. Rocamora, L. Vilella, L. Panadés‐De Oliveira, F. Álvarez‐Gómez, T. Ibáñez, A. Celdrán, G. Zimmermann, R. Zucca   +7 more
wiley   +1 more source

Epilepsy Risk Prediction Model For Patients With Tuberous Sclerosis Complex [PDF]

, 2020
BACKGROUND: Individuals with tuberous sclerosis complex are at increased risk of epilepsy. Early seizure control improves developmental outcomes, making identifying at-risk patients critically important.
Au, Kit Sing, TACERN Study Group, Northrup, Hope, Lupo, Philip J, Richard, Melissa A, Farach, Laura S, Wu, Joyce Y, Sahin, Mustafa, Krueger, Darcy A, Bebin, Elizabeth M   +9 more
core   +1 more source

Facilitating the timely diagnosis of Lennox–Gastaut syndrome: A checklist to support clinical practice

Epileptic Disorders, EarlyView.
Abstract Objective To develop and evaluate a simple‐to‐use checklist to support physicians with the timely diagnosis of Lennox–Gastaut syndrome (LGS). Methods A panel of 10 pediatric and adult epileptologists used the International League Against Epilepsy (ILAE) criteria for LGS classification and definition to develop seven questions for the checklist,
Nicola Specchio, Alexis Arzimanoglou, Stéphane Auvin, Antonio Gil‐Nagel, Lieven Lagae, Rima Nabbout, Susanne Schubert‐Bast, Adam Strzelczyk, Eugen Trinka, J. Helen Cross   +9 more
wiley   +1 more source

Rare manifestations and malignancies in tuberous sclerosis complex: findings from the TuberOus SClerosis registry to increAse disease awareness (TOSCA) [PDF]

, 2021
Manifestación rara; Tosca; Complejo de esclerosis tuberosaManifestació rara; Tosca; Complex d'esclerosi tuberosaRare manifestation; Tosca; Tuberous sclerosis complexBackground Tuberous sclerosis complex (TSC) is a rare multisystem autosomal dominant ...
Perkovic Benedik, Mirjana, Curatolo, Paolo, Cottin, Vincent, Sauter, Matthias, Macaya Ruíz, Alfons, Carter, Tom, Belousova, Elena   +6 more
core   +1 more source

Genetic testing among patients evaluated for epilepsy surgery

Epileptic Disorders, EarlyView.
Abstract Objective Genetic testing performed to identify the underlying etiology of epilepsy has become increasingly common and is now being recommended as part of the presurgical evaluation for epilepsy surgery. This study aimed to characterize the types of genetic tests performed in patients evaluated for epilepsy surgery and assess how genetic ...
Anni Saarela, Veera‐Julia Kuronen, Oskari Timonen, Leena Jutila, Katri Silvennoinen, Annemari Kilpeläinen, Jarkko Kirjavainen, Reetta Kälviäinen   +7 more
wiley   +1 more source

Managing Epilepsy in Tuberous Sclerosis Complex

, 2004
Epilepsy is very common in tuberous sclerosis complex and occurs in 80 to 90% of affected individuals during their lifetime. Onset usually occurs during childhood, and up to one third of children with tuberous sclerosis complex will develop infantile ...
Elizabeth Anne Thiele
core   +1 more source

Occipital irregular delta activity in focal epilepsy

Epileptic Disorders, EarlyView.
Abstract Objective Nonspecific occipital irregular delta activity (OID) is a common finding in focal epilepsy (FE). However, the significance of OID and its relationship to the underlying etiology of FE remain largely unstudied. This study aimed to investigate the relationship between OID and the etiology of FE, as well as the relationship between OID ...
Mónika Bessenyei, Miklós Emri, Johanna Dömötör, Béla Clemens   +3 more
wiley   +1 more source