Results 71 to 80 of about 6,413 (205)
Health Science Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background Leonurine (LEO), a bioactive alkaloid derived from the Leonurus genus, exhibits diverse pharmacological activities including uterotonic, antioxidant, anti‐inflammatory, antiapoptotic, Antitumor, and vasoprotective effects. This review aims to provide a comprehensive overview of LEO's pharmacokinetics, pharmacological mechanisms ...
Zhouyue Gu
wiley +1 more source
Structural basis of human zinc-activated channel (ZAC) signaling and modulation
Cell DiscoveryZinc (Zn2+) plays essential roles in a plethora of physiological processes, including key functions as a neuromodulator. The zinc-activated channel (ZAC) belongs to the Cys-loop receptor (CLR) superfamily of pentameric ligand-gated ion channels, which ...
Zixuan Zhou +8 more
doaj +1 more source
The Journal of Physiology, Volume 604, Issue 5, Page 2110-2130, 1 March 2026.Abstract figure legend During infection, prostaglandin E2 (PGE2) is produced and elicits warmth‐seeking behaviour and involuntary febrile responses by acting on prostaglandin EP3 receptors (EP3Rs) in two distinct brain sites. PGE2 acting on EP3Rs on neurons in the external lateral part of the lateral parabrachial nucleus (LPBel) augments cold sensory ...
Takaki Yahiro +2 more
wiley +1 more source
, 1982 균형마취란 강력한 진통제, 진정제와 함께 筋肉弛緩劑를 주입하여 마취를 시행하는 방법이다. 균형마취시 환자의 동통과 의식 소실을 위하여 강력한 진통제와 진정제인 meperidine, diazepam 사용과 함께 非脫分極性 筋肉弛緩劑인 d-tubocurarine 정맥 주입시 histamine 遊離로 인해 동반되는 혈압하강을 감소시키고자 d-tubocurarine(0.4 mg/kg)의 정맥 주입속도에 따른 심박수 및 혈압의 변화를 관찰하였다 ...
김경한.
core +1 more source
Reflex erection in the rat: reciprocal interplay between hemodynamic and somatic events
BMC Urology, 2018 Background Penile erection is a complex reflex under spinal control and modulated by the brain. The hemodynamic events under autonomic control and the perineal muscles somatic activity are interconnected during the reflex erection at the spinal level ...
Alexander Andreev-Andrievskiy +2 more
doaj +1 more source
The Journal of Physiology, Volume 604, Issue 5, Page 2083-2109, 1 March 2026.Abstract figure legend During the first few days of development, zebrafish acquire the ability to produce increasingly refined movements that rely progressively less on the activity of primary motoneurons. At the same time, primary motoneurons undergo functional maturation, becoming increasingly capable of repetitive firing.
Stephanie F. Gaudreau, Tuan V. Bui
wiley +1 more source
Advanced Science, Volume 13, Issue 7, 3 February 2026.This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley +1 more source
(+)-Tubocurarine is a potent inhibitor of cation channels in the vacuolar membrane of Chenopodium rubrum L [PDF]
, 1990 The effect of the acetylcholine antagonist and channel blocker (+)-tubocurarine on the calcium-dependent slow vacuolar (SV) cation channels in the tonoplast of suspension-cultured cells of Chenopodium rubrum L.
Weiser, T. +3 more
core +1 more source
Excitability changes in vasomotor areas of the brain stem following D-tubocurarine
, 1959 Cardiovascular responses to electrical stimulation of the medulla and hypothalamus have been studied before and after administration of d-tubocurarine.
John W. Manning, Clarence N. Peiss
core +1 more source