Results 161 to 170 of about 292,166 (345)

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

Advanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang   +10 more
wiley   +1 more source

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

Advanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen, Xiaoxiao Meng, Yong Zhu, Dapeng Wang, Mengmeng Wang, Ziyuan Wang, Xue Tian, Jiaxiang Zhang, Zhiying Yue, Zhengfeng Yang, Ruilan Wang   +10 more
wiley   +1 more source

Effect of antimitotic drugs on tubulin GTPase activity and self-assembly.

, 1979
T David-Pfeuty, C. Simon, Dominique Pantaloni   +2 more
openalex   +1 more source

Vasohibins/SVBP are tubulin carboxypeptidases (TCPs) that regulate neuron differentiation

Science, 2017
C. Aillaud, C. Bosc, Leticia Peris, A. Bosson, Pierre Heemeryck, J. Van Dijk, Julien Le Friec, Benoît Boulan, Frédérique Vossier, L. Sanman, S. Syed, Neri Amara, Y. Couté, L. Lafanechère, E. Denarier, C. Delphin, L. Pelletier, S. Humbert, M. Bogyo, A. Andrieux, Krzysztof Rogowski, M. Moutin   +21 more
semanticscholar   +1 more source

Tumor‐Associated Sympathetic Nerves Promote the Progression of Epstein‐Barr Virus‐Positive Diffuse Large B‐Cell Lymphoma

Advanced Science, EarlyView.
Sympathetic nerve innervation promotes the progression of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV+ DLBCL) via β2‐adrenergic receptors. The discovery of enhanced nerve infiltration and β2AR expression reveals a novel mechanism and highlights the sympathetic–β2AR axis as a promising target for therapeutic intervention in EBV+ DLBCL.
Silan Huang, Dexin Lei, Linbin Yang, Aiwei Bi, Yanlou Wang, Peng Zhang, Dongyu Zhuang, Honglian Liu, Qingqing Cai, Man Nie, Yi Xia   +10 more
wiley   +1 more source

Use of a GTP photoaffinity probe to resolve aspects of the mechanism of tubulin polymerization.

, 1979
Robert L. Geahlen, Boyd E. Haley
openalex   +1 more source

Role of nucleotides in tubulin polymerization: Effect of guanylyl 5′-methylenediphosphonate [PDF]

, 1978

openalex   +1 more source

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source

Nucleotide release from tubulin and nucleoside-5'-diphosphate kinase action in microtubule assembly.

, 1979
Brian Terry, D L Purich
openalex   +1 more source

Polymerization of purified tubulin by synthetic polycations [PDF]

, 1978
Sergey Kuznetsov, Vladimir I. Gelfand, Vladimir Rodionov, V.A. Rosenblat, J. G. Gulyaeva   +4 more
openalex   +1 more source