Results 181 to 190 of about 407,673 (329)
Quantitative determination of tubulin by radioimmunoassay [PDF]
, 1977 Marcel Joniau +3 more
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Advanced Science, EarlyView.IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu +16 more
wiley +1 more source
Effect of antimitotic drugs on tubulin GTPase activity and self-assembly.
, 1979 T David-Pfeuty +2 more
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Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Advanced Science, EarlyView.Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang +4 more
wiley +1 more source
Advanced Science, EarlyView.NDRG1 drives lactate accumulation and histone lactylation in lung adenocarcinoma, promoting immunosuppression via M2 macrophage polarization and CD8⁺ T cell inhibition. High NDRG1 expression correlates with poor prognosis, an immunosuppressive microenvironment, and immunotherapy resistance.
Gujie Wu +14 more
wiley +1 more source
Polycation-induced assembly of purified tubulin.
, 1976 Harold Erickson, William A. Voter
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Advanced Science, EarlyView.To solve the challenge of PROTACs in clinical potential due to poor water solubility and membrane permeability, a nanodelivery system based on lipid nanodisks loaded with MZ1 prodrug (LND‐MZ1) to remodel the physicochemical and pharmacokinetic properties of PROTAC MZ1 is elaborately proposed.
Meichen Pan +6 more
wiley +1 more source
Use of a GTP photoaffinity probe to resolve aspects of the mechanism of tubulin polymerization.
, 1979 Robert L. Geahlen, Boyd E. Haley
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