Results 21 to 30 of about 20,227 (269)
Angewandte Chemie, Volume 137, Issue 52, December 22, 2025.Hybrid physics and deep‐learning enabled design methods identified miniprotein binders to Flpp3 (Francisella‐like lipoprotein), a key virulence factor from Francisella tularensis. Multiple candidates with nanomolar to picomolar binding affinities were obtained using yeast surface display screening and further experimental optimization.
Gizem Gokce‐Alpkilic +18 more
wiley +2 more sources
Early Diagnosis of Tularemia by Flow Cytometry, Czech Republic, 2003–2015
Emerging Infectious Diseases, 2019 We retrospectively assessed the utility of a flow cytometry–based test quantifying the percentage of CD3+ T cells with the CD4–/CD8– phenotype for predicting tularemia diagnoses in 64 probable and confirmed tularemia patients treated during 2003–2015 and
Aleš Chrdle +9 more
doaj +1 more source
Low dose vaccination with attenuated Francisella tularensis strain SchuS4 mutants protects against tularemia independent of the route of vaccination. [PDF]
PLoS ONE, 2012 Tularemia, caused by the gram-negative bacterium Francisella tularensis, is a severe, sometimes fatal disease. Interest in tularemia has increased over the last decade due to its history as a biological weapon.
Dedeke Rockx-Brouwer +6 more
doaj +1 more source
Инфекция и иммунитет, 2021 Here we review the data on the global spread of tularemia — a natural focal, especially dangerous human and animal infection caused by the bacterium Francisella tularensis. Strains of the most virulent F. tularensis subspecies tularensis circulate solely
T. Yu. Kudryavtseva, A. N. Mokrievich
doaj +1 more source
Public Health Threat of New, Reemerging, and Neglected Zoonoses in the Industrialized World [PDF]
, 2010 Microbiologic infections acquired from animals, known as zoonoses, pose a risk to public health. An estimated 60% of emerging human pathogens are zoonotic. Of these pathogens, >71% have wildlife origins.
Cutler, S.J. +2 more
core +4 more sources
Complicated Ulceroglandular Tularemia
Journal of Global Infectious Diseases, 2022 A 52-year-old woman presented with a tender swelling in the right axilla, fever, a headache, nausea, and general weakness. On examination, she was found to have lymphangitis on the right arm and red papules on the 1st and 2nd fingers of the right hand. She had had prepared wild rabbit stew 5 days before disease onset. Serology
Branko Brmbolic +2 more
openaire +3 more sources
Frontiers in Cellular and Infection Microbiology, 2018 Francisella tularensis is a highly infectious Gram-negative bacterium that is the etiologic agent of tularemia in animals and humans and a Tier 1 select agent.
Tina Guina +8 more
doaj +1 more source
Current EpidemiologicaL Situation on Tularemia in the Northwestern Federal District of Russia
Эпидемиология и вакцинопрофилактика, 2016 Relevance. In Russia every year are registred 100 or more cases of tularemia, with about 70% of them in the Central, Northwest and Siberian federal districts. Goal.
T. N. Demidova +4 more
doaj +1 more source
Tularemia, a re-emerging infectious disease in Iran and neighboring countrie [PDF]
Epidemiology and Health, 2015 OBJECTIVES: Tularemia is a zoonotic disease transmitted by direct contact with infected animals and through arthropod bites, inhalation of contaminated aerosols, ingestion of contaminated meat or water, and skin contact with any infected material.
Afsaneh Zargar +2 more
doaj +1 more source
Re-emergence of tularemia in Germany: Presence of
, 2008 Background Tularemia re-emerged in Germany starting in 2004 (with 39 human cases from 2004 to 2007) after over 40 years of only sporadic human infections. The reasons for this rise in case numbers are unknown as is the possible reservoir of the etiologic
A Johansson +22 more
core +2 more sources