Results 71 to 80 of about 18,389 (170)

Data_Sheet_1_Immunopathology of Tumefactive Demyelinating Lesions-From Idiopathic to Drug-Related Cases.xlsx

, 2022
Tumefactive demyelinating lesions (TDL) represent a diagnostic dilemma for clinicians, and in rare atypical cases a collaboration of a neuroradiologist, a neurologist, and a neuropathologist is warranted for accurate diagnosis.
Maria-Evgenia Brinia (12241238), Aigli G. Vakrakou (12241235), Leonidas Stefanis (264252), Ioanna Svolaki (4972918), Theodore Argyrakos (12241241), Constantinos Kilidireas (700376)   +5 more
core   +1 more source

Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study

Annals of Clinical and Translational Neurology, Volume 12, Issue 8, Page 1566-1574, August 2025.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan, María A. Piedrabuena, María A. Zarate, Sofía Rodríguez Murúa, Ezequiel I. Surace, Mauricio F. Farez, Marcela P. Fiol, María C. Ysrraelit, Jorge Correale   +8 more
wiley   +1 more source

Value of 18F-FET PET in Patients With Suspected Tumefactive Demyelinating Disease-Preliminary Experience From a Retrospective Analysis [PDF]

, 2018
PURPOSE To investigate the diagnostic value of F-fluoroethyl-L-tyrosine (FET) positron emission tomography (PET) in patients with suspected tumefactive demyelinating disease.
Schreiner, Simon, Hayward-Könnecke, Helen K, Albatly, Abdulrahman A, Simon Schreiner, Helen K. Hayward-Könnecke, Spyros S. Kollias, Alfred Buck, Barbagallo, Massimo, Abdulrahman A. Albatly, Kollias, Spyros S, Massimo Barbagallo, Huellner, Martin W, Martin W. Huellner, Buck, Alfred   +13 more
core   +1 more source

Tumefactive Demyelination Presenting as an Intracranial Space-occupying Lesion: A Diagnostic Challenge

Apollo Medicine
Objectives: Tumefactive demyelination is a rare form of multiple sclerosis which is characterised by solitary, acute, demyelinating lesions in the central nervous system, usually larger than 2 cm, accompanied by surrounding oedema.
Nayaab Saeed, Pushpendra Nath Renjen, Dinesh Mohan Chaudhari, Mohd Amaan Mahmood, Avinash Goswami   +4 more
doaj   +1 more source

Semliki Forest virus induced, immune mediated demyelination: the effect of irradiation [PDF]

, 1987
Intraperitoneal infection with the avirulent A7(74) strain of the alphavirus Semliki Forest virus (SFV) induces an immune mediated demyelinating encephalomyelitis.
Fazakerley, J K, Webb, H E
core  

Table_1_Immunopathology of Tumefactive Demyelinating Lesions-From Idiopathic to Drug-Related Cases.DOCX

, 2022
Tumefactive demyelinating lesions (TDL) represent a diagnostic dilemma for clinicians, and in rare atypical cases a collaboration of a neuroradiologist, a neurologist, and a neuropathologist is warranted for accurate diagnosis.
Maria-Evgenia Brinia (12241238), Aigli G. Vakrakou (12241235), Leonidas Stefanis (264252), Ioanna Svolaki (4972918), Theodore Argyrakos (12241241), Constantinos Kilidireas (700376)   +5 more
core   +1 more source

Multifaceted Biomarkers Suggest a Similar Profile of CNS Pathology in Relapsing and Progressive MS

European Journal of Neurology, Volume 32, Issue 2, February 2025.
ABSTRACT Background Relapsing–remitting (RR) and primary progressive (PP) multiple sclerosis (MS) have distinct clinical courses, but underlying pathophysiological differences remain unclear. We compared pathological components between RRMS, PPMS, and other inflammatory and neurodegenerative disorders, leveraging soluble biomarkers and post‐mortem ...
Katelijn M. Blok, Romy A. M. Klein Kranenbarg, Kirtana Ananth, Hendrik J. Engelenburg, Aletta van den Bosch, Lucia A. A. Giannini, Janet de Beukelaar, Harro Seelaar, Inge Huitinga, Ari Green, Beatrijs Wokke, Ahmed Abdelhak, Joost Smolders   +12 more
wiley   +1 more source

Tumefactive demyelinating lesions: Characteristics of individual lesions, individual patients, or a unique disease entity?

, 2015
Whether or not recurrent tumefactive demyelinating lesions are a unique form of CNS demyelinating disease or part of the continuum of multiple sclerosis is a question raised by the case report on which this commentary is based.
Weinshenker, B. G.
core   +1 more source

Chronic active lesions preferentially localize in watershed territories in multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 11, Issue 11, Page 2912-2922, November 2024.
Abstract Objective Paramagnetic rim lesions (PRLs) are a biomarker of chronic active lesions (CALs), and an important driver of neurological disability in multiple sclerosis (MS). The reason subtending some acute lesions evolvement into CALs is not known. Here we ask whether a relatively lower oxygen content is linked to CALs.
Ahmad A. Toubasi, Jarrod J. Eisma, Jiacheng Wang, Habeeb F. Kazimuddin, Bryan Hernandez, Taegan Vinarsky, Caroline Gheen, Zachary Rohm, Carynn Koch, Margareta A. Clarke, Rachael Cheek, John Kramer, James Eaton, Manus J. Donahue, Francesca Bagnato   +14 more
wiley   +1 more source

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Encephalitis among the Pediatric Intensive Care Unit Patients: A Comprehensive Clinical Review [PDF]

Zagazig University Medical Journal
Background: Myelin oligodendrocyte glycoprotein antibody-associated encephalitis (MOGAE) is an increasingly recognized entity within the MOG antibody-associated disease spectrum in children.
Zienab Mohamed, Dalia Abdelrahman, Ayman Marei, Mohamed Abdellatif Mohamed   +3 more
doaj   +1 more source