Results 151 to 160 of about 24,022 (284)

Responsive nitric oxide‐releasing antibacterial materials for biofilm‐associated infections: Mechanisms, design strategies, and applications

Responsive Materials, EarlyView.
This review summarizes the recent progress in responsive NO‐releasing materials and their applications in biofilm‐associated infectious diseases. The design principles and response mechanisms are given to provide inspiration toward the future development of multi‐responsive NO‐releasing materials.
Wenyue Sun, Meiqi Li, Di Nan, Jiaqi Zhao, Yu Chen, Yao Gao, Shichen Zhang, Kirsten L. Van Landuyt, Manlin Qi   +8 more
wiley   +1 more source

Approaching Gold‐Standard Sensitivity in a Portable and Versatile Gold Nanoprisms Thermoplasmonic Platform for Lateral Flow Detection of Biomolecules

Small, EarlyView.
This study presents a plasmonic thermal lateral flow (ThermoLFA) biosensor for ultrasensitive, early detection of biomolecules. By combining plasmonic gold nanoprisms (AuNPrs) and near‐infrared (NIR) laser activation, it enhances signal output beyond conventional LFAs.
Carlos Cuestas Ayllón, Alba Martín Barreiro, África García Barrientos, María Moros, Valeria Grazú Bonavía, Jesús Martínez de la Fuente   +5 more
wiley   +1 more source

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

Small, EarlyView.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

Whole‐transcriptome sequencing analyses identified exosomal circular RNAs in the plasma of pancreatic cancer patients as novel blood‐based biomarkers of disease

VIEW, EarlyView.
Pancreatic cancer (PaCa) has a poor prognosis, with low resection rates and high relapse rates, highlighting the urgent need for novel diagnostic biomarkers. Here, we performed whole‐transcriptome sequencing of plasma‐derived exosomes from PaCa patients and identified several differentially expressed circular RNAs (circRNAs).
Xiaomeng He, Yang Di, Lixiang Sun, Zhirong Wu, Mengting Luo, Xin Zhang, Huaqin Sun, Wanli Xu, Wenchuan Wu, Boheng Zhang, Jin Wang   +10 more
wiley   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Recent progress on the development of hydrogel‐based microneedles for transdermal drug delivery

VIEW, EarlyView.
This study provides a comprehensive and up‐to‐date analysis of recent progress in HMN technology, covering fundamental transdermal delivery mechanisms and design principles, biomaterials used in HMN fabrication, drug loading and release strategies, and emerging therapeutic applications.
Mohammad Muhtasim Ittisaf, Salman Farsi Taharat, Md. Sadek Miah, Hasan Tasnim Salehin, M. Azam Ali, Shoeb Ahmed   +5 more
wiley   +1 more source

Apo10 and TKTL1 as novel liquid biopsy biomarkers for early detection of gastrointestinal malignancies

VIEW, EarlyView.
(A) Overview of the study population and schematic illustration showing tumor‐derived apoptotic and metabolic biomarkers, Apo10 and TKTL1, being phagocytosed by circulating monocytes and subsequently detected in peripheral blood. (B) Illustration of the epitope detection in monocytes (EDIM) strategy, using a flow‐cytometric gating approach based on ...
Zhiying Mao, Qiyu Huang, Juan Xiao, Ziyu Liu, Xinyan Zou, Yuying Liu, Lizhi Liu, Musheng Zeng, Chuanbo Xie   +8 more
wiley   +1 more source

Seromucinous borderline ovarian tumors: Clinical and ultrasound characteristics and association with endometriosis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Seromucinous borderline ovarian tumors frequently appear as unilateral, left‐sided cysts with ground‐glass echogenicity and moderately vascularized solid components. Their strong association with ipsilateral endometriosis provides crucial sonographic and clinical clues for an accurate preoperative diagnosis.
Simona Del Forno, Marisol Doglioli, Chiara Landolfo, Giovanna Palomba, Claudia Vicenzi, Matilde Antonelli, Lucia De Meis, Francesca Govoni, Roberto Paradisi, Diego Raimondo, Renato Seracchioli   +10 more
wiley   +1 more source

Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy

Alimentary Pharmacology &Therapeutics, EarlyView.
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins, Srinivas Kamath, Rachel H. Davis, Samuel P. Costello, Robert V. Bryant, Alice S. Day, Paul Joyce   +6 more
wiley   +1 more source

Integrating ReSET with glycosyl iodide glycosylation in step-economy syntheses of tumor-associated carbohydrate antigens and immunogenic glycolipids. [PDF]

J Org Chem, 2014
Hsieh HW, Schombs MW, Gervay-Hague J.
europepmc   +1 more source