Results 231 to 240 of about 93,268 (298)

Tumor-Infiltrating Lymphocyte Scoring in Neoadjuvant-Treated Breast Cancer. [PDF]

Cancers (Basel)
Thomas N, Garaud S, Langouo M, Sofronii D, Boisson A, De Wind A, Duwel V, Craciun L, Larsimont D, Awada A, Willard-Gallo K.   +10 more
europepmc   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Tumor-Infiltrating Lymphocyte Therapy for Melanoma and Other Solid Tumors: Looking Back, Yet Moving Forward. [PDF]

Transplant Cell Ther
Shoushtari AN, Powell DJ.
europepmc   +1 more source

A novel mouse model of chronic Pseudomonas aeruginosa infection inducing bronchiectasis‐like phenotype

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract highlights a bronchiectasis mouse model driven by chronic Pseudomonas aeruginosa (CPA)‐loaded agar beads plus papain, which reproduces significant airway structural damage, inflammation, mucous overproduction, and functional impairment, providing a clinically relevant platform for studying disease mechanisms and evaluating ...
Heng Yang, Yang Liu, Yuqing Wang, Yuhua Wen, Yan Chen, Rui Fan, Jiayan Xu, Shunlian Hu, Hao Qian, Rui Jiang, Weijun Cao, Jinfu Xu   +11 more
wiley   +1 more source

Advances in Tumor-Infiltrating Lymphocyte (TIL) as a Prognostic Factor and for Treating Invasive Cutaneous Melanoma. [PDF]

Int J Mol Sci
de Oliveira GAF, de Oliveira DA, Nisimoto MYSM, Rubinho R, Gomes HC, Marti LC, de Oliveira Filho RS.   +6 more
europepmc   +1 more source

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello, Mario Picozza, Gisella Guerrera, Silvia Corbisiero, Andrea Misiti, Roberta C. Placido, Alice Verdiani, Lorenzo de Marco, Manolo Sambucci, Elena Olivieri, Daniela F. Angelini, Esmeralda Quartuccio, Luca Prosperini, Carla Tortorella, Maria C. Buscarinu, Valeria Zancan, Francesca de Masi, Marco Salvetti, Claudio Gasperini, Giovanna Borsellino, Luca Battistini   +20 more
wiley   +1 more source

Unveiling the Landscape of PD-L1 Expression and Tumor-Infiltrating Lymphocyte Subtypes in Advanced Triple-Negative Breast Cancer in Brazil. [PDF]

Breast Cancer (Dove Med Press)
Dos Santos ALS, Da Silva JL, De Albuquerque LZ, Neto ALA, Da Silva CF, Cerva LAM, Small IA, Rodrigues FR, De Macedo FC, Marcelino CP, Batista PM, Rego MADC, Borba MACSM, De Melo AC.   +13 more
europepmc   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

CRISPR/Cas9-mediated PD-1 attenuation enhances tumor infiltrating lymphocyte-based adoptive cellular therapy in humanized-PDX model of hepatocellular carcinoma. [PDF]

Transl Oncol
Ge W, Liu H, Wu D, Hu Y, Liang Q, Liu M, Liu H, Wu J, Zhang J, Deng Y, Ghimire K, Rong P, Wang W, Ma X.   +13 more
europepmc   +1 more source

Selenium Nanomaterials for Wound Healing: Synergistic Strategies from Anti‐Infection to Tissue Regeneration

Advanced NanoBiomed Research, EarlyView.
Selenium nanoparticles (SeNPs) are emerging as multifunctional platforms for wound healing, integrating antimicrobial, anti‐inflammatory, and proregenerative activities. This review summarises key mechanisms and recent advances in SeNP‐enabled composite dressings, immunomodulatory nanocomposites, microenvironment‐responsive hydrogels, photothermal and ...
Yangxia Chen, Xiaoshuang Liang, Sirui Li, Shuoshan Li, Wei Liu, Yingping Lin, Siqi Li, Zehang Zhang, Judun Zheng, Tianfeng Chen, Rongyi Chen   +10 more
wiley   +1 more source