Results 151 to 160 of about 159,317 (346)

Enhancement of T Cell Receptor Signaling of Tumor‐infiltrating Lymphocytes by Retrovirally Mediated fyn Gene Transduction [PDF]

, 1994
Kazuyuki Fujita, Hirokazu Ikarashi, Koichi Takakuwa, Shoji Kodama, Tsuyoshi Akagi, Tadashi Yamamoto, Kenichi Tanaka   +6 more
openalex   +1 more source

Organic AIE Nanoradiosensitizer Potentiates X‐Ray Triggered Continuous Reactive Oxygen Species Generation for Potent Cancer Radioimmunotherapy

Advanced Materials, EarlyView.
Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu, Minmin Zhang, Qinqin Huang, Song Gao, Sitong Chu, Qi Li, Wanyao Chen, Xinglong Zhang, Tianfu Zhang, Ben Zhong Tang, Shipeng Ning   +10 more
wiley   +1 more source

Self‐Powered α Radionuclide Nanomedicine: Mitochondria‐Targeted Multimodal Energy Recycling for Amplified Radioimmunotherapy

Advanced Materials, EarlyView.
A multifunctional nanomedicine co‐loading of the α‐emitter 223RaCl2 within iron‐based MOFs is developed. Precisely targeted to mitochondria, it exploits the full decay spectrum to synchronize three therapeutic actions: direct α‐particle ionization, self‐powered catalytic H2O2 generation via secondary electrons, and immunogenic cell death induction ...
Xian Li, Chaochao Wang, Yelin Wu, Jiajia Zhang, Han Zhang, Shanshan Qin, Linglin Tang, Fei Yu   +7 more
wiley   +1 more source

The Fas Counterattack In Vivo: Apoptotic Depletion of Tumor-Infiltrating Lymphocytes Associated with Fas Ligand Expression by Human Esophageal Carcinoma [PDF]

, 1998
Michael Bennett, Joe O’Connell, Gerald C. O’Sullivan, Ciaran Brady, Desmond Roche, John Collins, Fergus Shanahan   +6 more
openalex   +1 more source

GelMA/AgNWs Hydrogel Combined with Electrical Stimulation Effectively Promotes Skin Wound Healing

Advanced Materials Interfaces, EarlyView.
The doped AgNWs in GelMA hydrogel prevent the wound from being infected and introduce the electrical field into the wound region. COMSOL simulation guides the introduced electric field to be conducive to promoting cell migration and proliferation. Thus, the GelMA/AgNWs hydrogel combined with ES effectively accelerated the healing process of skin wounds.
Xiaoxuan Hou, Yujie Wang, Mengni Zhu, Jie Zhang, Hongxin Qi, Min Xu, Xianghui Wang   +6 more
wiley   +1 more source

Effect of indomethacin on tumor-infiltrating lymphocytes of a spontaneously developed murine mammary adenocarcinoma

, 1989
Tsu-Yi Chao, T. Ming Chu
openalex   +2 more sources

Identification of a gene encoding a melanoma tumor antigen recognized by HLA-A31-restricted tumor-infiltrating lymphocytes. [PDF]

, 1995
R F Wang, Paul F. Robbins, Yutaka Kawakami, Xiaojun Kang, Steven A. Rosenberg   +4 more
openalex   +1 more source

Mechanical Interactions Impact the Functions of Immune Cells and Their Application in Immunoengineering

Advanced Therapeutics, EarlyView.
This review covers the mechanical forces experienced by immune cells through cell–cell and cell–extracellular matrix interactions and how these forces influence their receptors and functions. These relationships between forces and cellular functions can be exploited using engineering techniques to modify the physical properties of materials for novel ...
Yu‐Chang Chen, Nghi M. Tran, Kyle H. Vining   +2 more
wiley   +1 more source

Analysis of T-cell-receptor ?-chain-gene usage in peripheral-blood and tumor-infiltrating lymphocytes from human non-small-cell lung carcinomas [PDF]

, 1999
Hamid Echchakir, Carine Asselin‐Paturel, Guillaume Dorothée, Isabelle Vergnon, Dominique Grunenwald, Salem Chouaı̈b, Fathia Mami‐Chouaib   +6 more
openalex   +1 more source

Microphysiological Systems in Cancer Research: Advancing Immunotherapy through Tumor Microenvironment‐Integrated Organ‐On‐Chip Models

Advanced Therapeutics, EarlyView.
Emerging microphysiological systems reproduce the spatial, biochemical, and cellular complexity of the tumor microenvironment, surpassing 2D cultures and murine models. By integrating patient‐derived tumors, perfusable vasculature, and immune trafficking, these organ‐on‐chip platforms reveal mechanisms of immune evasion, predict therapeutic responses ...
Fabiana Moresi, Francesco Noto, Jyothsna Vasudevan, Xavier Bisteau, Giulia Adriani, Andrea Pavesi   +5 more
wiley   +1 more source