Results 91 to 100 of about 3,691,927 (315)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Escape from immunotherapy: possible mechanisms that influence tumor regression/progression [PDF]
, 2004 Tumor escape is one major obstacle that has to be addressed prior to designing and delivering successful immunotherapy. There is compelling evidence to support the notion that immunogenic tumors, in murine models and cancer patients, can be rejected by ...
Ahmad, M, Ali, SA, Rees, RC
core +1 more source
Crosstalk between Thyroid Carcinoma and Tumor-Correlated Immune Cells in the Tumor Microenvironment
, 2023 Thyroid cancer (TC) is the most common malignancy in the endocrine system. Although most TC can achieve a desirable prognosis, some refractory thyroid carcinomas, including radioiodine-refractory differentiated thyroid cancer, as well as anaplastic ...
Mingyuan Song +3 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Fighting tumors with tumors [PDF]
Science-Business eXchange, 2011 Researchers at The Rogosin Institute have used cancer cell–containing agarose beads to inhibit tumor proliferation in animals. The beads already are in an investigator-sponsored Phase II trial in patients with pancreatic cancer, advanced colorectal cancer or refractory prostate cancer.
openaire +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Expert consensus on population-based
Zhongguo aizheng zazhiGermline mutations in BRCA genes (including BRCA1/2) are the major risk factors for hereditary tumors including breast and ovarian cancer. Population based BRCA gene screening, particularly in high-risk individuals with a family history of cancer, can ...
Anti-Cancer Association Tumor Biomarker Professional Committee China +1 more
doaj
A tumor asszociált sztrómát célzó terápiák a rákgyógyításban
, 2023 Diplomadolgozatom megírása közben igyekeztem az immunrendszer legfontosabb tulajdonságait kihangsúlyozni, amelyek befolyásolják a tumor ellenes immunválasz kialakulását. A természetes és a szerzett immunrendszer egymással szoros együttműködésben veszi
Tóth, Melinda
core
Strategies for Efficient Targeting of Tumor Collagen for Cancer Therapy
, 2022 The tumor stroma, which comprises stromal cells and non-cellular elements, is a critical component of the tumor microenvironment (TME). The dynamic interactions between the tumor cells and the stroma may promote tumor progression and metastasis and ...
Gabriele Toietta +7 more
core +1 more source