Results 101 to 110 of about 8,099,813 (387)

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Cardiac tumors

Journal of Cardiovascular Echography, 2020
Cardiac tumors (CTs) are extremely rare, with an incidence of approximately 0.02% in autopsy series. Primary tumors of the heart are far less common than metastatic tumors. CTs usually present with any possible clinical combination of heart failure, arrhythmias, or embolism.
Grazia Casavecchia, Chiara Lestuzzi, Matteo Gravina, Giovanni Corrado, Maurizio Tusa, Natale D. Brunetti, Vincenzo Manuppelli, Ines Paola Monte   +7 more
openaire   +5 more sources

Tumor lamination in mediastinal giant tumors [PDF]

Revista do Colégio Brasileiro de Cirurgiões, 2017
ABSTRACT Mediastinum tumors may grow slowly and reach giant proportions without symptoms, hindering surgical removal. Tumor big dimensions difficult surgical maneuvers, with risk of uncontrollable bleeding and prejudice to surrounding structures. It may be necessary the use of exceptional measures such as venous-venous circulatory deviation, pre ...
Alexandre Ciappina Hueb, Rafael Diniz Abrantes, Elias Kallás   +2 more
openaire   +4 more sources

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Tumor angiogenesis: causes, consequences, challenges and opportunities

Cellular and Molecular Life Sciences, 2019
Tumor vascularization occurs through several distinct biological processes, which not only vary between tumor type and anatomic location, but also occur simultaneously within the same cancer tissue. These processes are orchestrated by a range of secreted
R. Lugano, Mohanraj Ramachandran, A. Dimberg   +2 more
semanticscholar   +1 more source

Portal vein thrombosis and arterioportal shunts : effects on tumor response after chemoembolization of hepatocellular carcinoma [PDF]

, 2011
AIM: To evaluate the effect of portal vein thrombosis and arterioportal shunts on local tumor response in advanced cases of unresectable hepatocellular carcinoma treated by transarterial chemoembolization.
Abdelaziz, Omar, Ackermann, Hans, Emad-Eldin, Sally, Mohammed, Nour-Eldin Abdelrehim Nour-Eldin, Naguib, Nagy Naguib Naeem, Trojan, Jörg, Vogl, Thomas J.   +6 more
core   +2 more sources

Role of Sphingosylphosphorylcholine in Tumor and Tumor Microenvironment [PDF]

Cancers, 2019
Sphingosylphosphorylcholine (SPC) is a unique type of lysosphingolipid found in some diseases, and has been studied in cardiovascular, neurological, and inflammatory phenomena. In particular, SPC's studies on cancer have been conducted mainly in terms of effects on cancer cells, and relatively little consideration has been given to aspects of tumor ...
Mi Kyung Park, Chang-Hoon Lee
openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma.

New England Journal of Medicine, 1991
BACKGROUND Experimental evidence suggests that the growth of a tumor beyond a certain size requires angiogenesis, which may also permit metastasis.
N. Weidner, J. Semple, W. Welch, J. Folkman   +3 more
semanticscholar   +1 more source

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis [PDF]

, 2011
Macrophages abundantly found in the tumor microenvironment enhance malignancy(1). At metastatic sites a distinct population of metastasis associated macrophages (MAMs) promote tumor cell extravasation, seeding and persistent growth(2).
AB Al-Mehdi, AD Borowsky, AJ Minn, AM Havens, B Brandt, B Qian, Bin-Zhi Qian, BS Nielsen, DR Getts, DR Rhodes, Elizabeth A. Kaiser, F Geissmann, F Geissmann, F Geissmann, FK Swirski, H Saji, HP Gerber, Hui Zhang, Jeffrey W. Pollard, JH Im, Jinghang Zhang, Jiufeng Li, JM Carton, Liam R. Campion, Linda A. Snyder, MD Abramoff, P Stern, P Tsui, RT Palframan, T Ueno, T Valkovic, Takanori Kitamura, Y Huang   +32 more
core   +2 more sources