Results 111 to 120 of about 8,099,813 (387)
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Journal of Obstetrics and Gynaecology, 2023 This study aimed to elucidate the differences in vulval squamous cell carcinomas (VSCC) based on the HPV infection status. The sequencing data GSE183454 which contains 23 VSCC samples based on its HPV infection status was obtained from the Gene ...
Ruxing Xi +7 more
doaj +1 more source
Gasdermin E suppresses tumor growth by activating anti-tumor immunity
Nature, 2020 Cleavage of the gasdermin proteins to produce pore-forming amino-terminal fragments causes inflammatory cell death (pyroptosis)1. Gasdermin E (GSDME, also known as DFNA5)—mutated in familial ageing-related hearing loss2—can be cleaved by caspase 3 ...
Zhibin Zhang +13 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens +8 more
wiley +1 more source
Scientific ReportsLong non-coding RNAs (lncRNAs), such as SNHG6, have been identified as crucial regulators in the progression of various cancers, including esophageal squamous cell carcinoma (ESCC).
Jiali Wang +6 more
doaj +1 more source
Mathematical modeling of tumor therapy with oncolytic viruses: Effects of parametric heterogeneity on cell dynamics [PDF]
, 2006 One of the mechanisms that ensure cancer robustness is tumor heterogeneity, and its effects on tumor cells dynamics have to be taken into account when studying cancer progression.
Karev, Georgy P. +2 more
core +4 more sources
Journal of the Belgian Society of Radiology, 2015 A 54-year-old woman presented with a two-year-history of tenderness and cold sensitivity of the subungueal region of her 3 left finger. Physical examination revealed a pinkish red spot under the nail. Ultrasonography of the 3 left finger shows a well-delimited hypoechoic and hypervascularised mass in the subungueal area (Fig. A).
Ahmed Larbi +4 more
openaire +6 more sources
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Journal of Hematology & Oncology, 2018 Background Immune checkpoint inhibitors have led to a breakthrough in solid tumor immunotherapy, but related studies on musculoskeletal tumors are few, especially for PD-L2.
Bingxin Zheng +7 more
doaj +1 more source
Medical Immunology, 2018 The immune system has effectively evolved to protect the host against foreign invaders, including bacterial, viral, and parasitic infiltrates. Less clear has been the interaction and the protective effects the immune system mounts against its own ...
Rachel L. G. Maus +2 more
semanticscholar +1 more source