Results 31 to 40 of about 5,944,302 (351)

The malignancy of chordomas is enhanced via a circTLK1/miR-16-5p/Smad3 positive feedback axis

Cell Death Discovery, 2023
CircRNAs play crucial roles in various malignancies via an increasing number of reported regulatory mechanisms, including the classic sponging mechanism between circRNAs and micro RNAs (miRNAs). We performed bioinformatic analyses and identified circTLK1
Jingbing Lou, Hongliang Zhang, Qingshan Huang, Chenglong Chen, Wei Wang, Jianfang Niu, Jiuhui Xu, Tingting Ren, Yi Huang, Xiaodong Tang, Wei Guo   +10 more
doaj   +1 more source

The importance of circulating tumor products as „liquid biopsies” in colorectal cancer [PDF]

, 2018
Liquid biopsies represent an array of plasma analysis tests that are studied to evaluate and identify circulating tumor products, especially circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA).
Calborean, Veronica, Miscoci, Alina, Pirvu, Cristian D., Pădureanu, Vlad, Rogoveanu, Otilia C., Streba, Costin T., Vere, Cristin C.   +6 more
core   +4 more sources

The Application of PET/CT in Predicting and Evaluating the Therapeutic Response in Chemotherapy of Solid Tumor

Journal of Isotopes, 2017
Three aspects of the application of PET/CT in solid tumor chemotherapy were summarized, including the selection of evaluation criteria, the proper time of using PET/CT in the evaluation and the parameters of PET/CT in evaluating the response of ...
positron emission tomography solid tumor chemotherapy predicton of therapeutic response
doaj   +1 more source

RUNX3-mediated circDYRK1A inhibits glutamine metabolism in gastric cancer by up-regulating microRNA-889-3p-dependent FBXO4

Journal of Translational Medicine, 2022
Background Targeting glutamine metabolism is previously indicated as a potential and attractive strategy for gastric cancer (GC) therapy. However, the underlying mechanisms responsible for the modification of glutamine metabolism in GC cells have not ...
Haofeng Liu, Qiu Xue, Hongzhou Cai, Xiaohui Jiang, Guangxin Cao, Tie Chen, Yuan Chen, Ding Wang   +7 more
doaj   +1 more source

Direct contact between Plasmodium falciparum and human B-cells in a novel co-culture increases parasite growth and affects B-cell growth

Malaria Journal, 2021
Background Plasmodium falciparum parasites cause malaria and co-exist in humans together with B-cells for long periods of time. Immunity is only achieved after repeated exposure.
Sreenivasulu B. Reddy, Noemi Nagy, Caroline Rönnberg, Francesca Chiodi, Allan Lugaajju, Frank Heuts, Laszlo Szekely, Mats Wahlgren, Kristina E. M. Persson   +8 more
doaj   +1 more source

Long non-coding RNA NORAD/miR-224-3p/MTDH axis contributes to CDDP resistance of esophageal squamous cell carcinoma by promoting nuclear accumulation of β-catenin

Molecular Cancer, 2021
Background Cis-diamminedichloro-platinum (CDDP)-based chemotherapy regimens are the most predominant treatment strategies for patients with esophageal squamous cell carcinoma (ESCC).
Yunlong Jia, Cong Tian, Hongyan Wang, Fan Yu, Wei Lv, Yuqing Duan, Zishuo Cheng, Xuexiao Wang, Yu Wang, Tianxu Liu, Jiali Wang, Lihua Liu   +11 more
doaj   +1 more source

GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity. [PDF]

, 2016
Abnormal activation of the epidermal growth factor receptor (EGFR) due to a deletion of exons 2-7 of EGFR (EGFRvIII) is a common alteration in glioblastoma (GBM). While this alteration can drive gliomagenesis, tumors harboring EGFRvIII are heterogeneous.
David James, C, Engler, Jane R, Ewald, Andrew J, Gong, Henry, Huillard, Emmanuelle, Koshkakaryan, Gayane, Lindberg, Olle R, McKinney, Andrew, Molinaro, Annette M, Phillips, Joanna J, Robinson, Aaron E, Shieh, Joseph T   +11 more
core   +1 more source

Surgical Treatment and Proposed Modified Classification for Harrington Class III Periacetabular Metastases

Orthopaedic Surgery, 2021
Objectives This study aims to: (i) evaluate the outcome of patients with Harrington class III lesions who were treated according to Harrington classification; (ii) propose a modified surgical classification for Harrington class III lesions; and (iii ...
Ran Wei, Chiao Yee Lim, Yi Yang, Xiao‐dong Tang, Tai‐qiang Yan, Rong‐li Yang, Wei Guo   +6 more
doaj   +1 more source

Base composition of DNA in adenovirus-12-induced tumor [PDF]

, 1969
A series of experiments was conducted to study the base composition of DNA in AVl2-induced tumor and host cells by paper chromatography, and it was found that DNA per cent. guanine-cystosine contents were around 42 % in both of them. The base composition
Ohmori, Masaki
core   +1 more source

Tumor isoimmunity [PDF]

Experientia, 1958
Einige neue Ergebnisse auf dem Gebiete der Tumor-Immunitat werden mit der Literatur in Einklang gebracht, und eine Hypothese zur spontanen Tumorbildung wird vorgeschlagen. Ferner wird auf die Notwendigkeit eingegangen, bei Tumor-Isoimmunitats-Experimenten Spontantumoren zu verwenden an Stelle von lange transplantierten, vonin vitro entstandenen oder ...
openaire   +2 more sources