Results 31 to 40 of about 8,155,772 (355)

Sentinel Lymph Node Status is a Main Prognostic Parameter Needful for the Correct Staging of Patients with Melanoma Thicker than 4 mm: Single-Institution Experience and Literature Meta-Analysis

Journal of Investigative Surgery, 2019
Purpose of the study: The usefulness of sentinel lymph node biopsy in thick melanomas is debated. The aim of this study was to evaluate the possible prognostic significance of sentinel lymph node biopsy in T4 melanoma patients and to verify whether this ...
Borgognoni L, Sestini S, Gerlini G, Brandani P, Chiarugi C, Gelli R, Giannotti V, Crocetti E   +7 more
doaj   +1 more source

Expression of Programmed Cell Death 1 and Lymphocyte Activation Gene 3 in Perioperation of Adenocarcinoma of Esophagogastric Junction and Related Significance

Zhongliu Fangzhi Yanjiu, 2019
Objective To evaluate the expression of programmed cell death 1 (PD-1) and lymphocyte activation gene 3 (LAG-3) in lymphocytes following surgery for advanced adenocarcinoma of esophagogastric junction(AEGJ), and to understand the effect of radical ...
ZHANG Wei, LI Shoumiao, GONG Yanxin, LI Baozhong, ZHANG Zhizhong, LIU Zhiqiang   +5 more
doaj   +1 more source

Tumor Hypoxia and Circulating Tumor Cells [PDF]

International Journal of Molecular Sciences, 2020
Circulating tumor cells (CTCs) are a rare tumor cell subpopulation induced and selected by the tumor microenvironment’s extreme conditions. Under hypoxia and starvation, these aggressive and invasive cells are able to invade the lymphatic and circulatory systems.
Tinganelli W., Durante M.
openaire   +5 more sources

Macrophages-derived exosomal lncRNA LIFR-AS1 promotes osteosarcoma cell progression via miR-29a/NFIA axis

Cancer Cell International, 2021
Background Osteosarcoma (OS) is the most common primary malignant bone tumor in young people. Tumor-associated macrophages (TAMs) have been reported to play an important role in the development of osteosarcoma.
Hongliang Zhang, Yiyang Yu, Jun Wang, Yu Han, Tingting Ren, Yi Huang, Chenglong Chen, Qingshan Huang, Wei Wang, Jianfang Niu, Jingbing Lou, Wei Guo   +11 more
doaj   +1 more source

Essential gene pathways for glioblastoma stem cells: clinical implications for prevention of tumor recurrence. [PDF]

, 2011
Glioblastoma (World Health Organization/WHO grade IV) is the most common and most aggressive adult glial tumor. Patients with glioblastoma, despite being treated with gross total resection and post-operative radiation/chemotherapy, will almost always ...
Choe, Jinny, Liau, Linda M, Liu, Yue, Tso, Cho-Lea, Tso, Jonathan, Yamada, Kazunari, Ye, Fei   +6 more
core   +1 more source

RUNX3-mediated circDYRK1A inhibits glutamine metabolism in gastric cancer by up-regulating microRNA-889-3p-dependent FBXO4

Journal of Translational Medicine, 2022
Background Targeting glutamine metabolism is previously indicated as a potential and attractive strategy for gastric cancer (GC) therapy. However, the underlying mechanisms responsible for the modification of glutamine metabolism in GC cells have not ...
Haofeng Liu, Qiu Xue, Hongzhou Cai, Xiaohui Jiang, Guangxin Cao, Tie Chen, Yuan Chen, Ding Wang   +7 more
doaj   +1 more source

The influence of anisotropic growth and geometry on the stress of solid tumors [PDF]

, 2017
Solid stresses can affect tumor patho-physiology in at least two ways: directly, by compressing cancer and stromal cells, and indirectly, by deforming blood and lymphatic vessels.
Bravo-Castillero, Julián, Conci, Aura, García-Reimbert, Catherine, Guinovart-Díaz, Raúl, Merodio, José, Penta, Raimondo, Ramírez-Torres, Ariel, Rodríguez-Ramos, Reinaldo, Sabina, Federico J., Sevostianov, Igor   +9 more
core   +1 more source

The Application of PET/CT in Predicting and Evaluating the Therapeutic Response in Chemotherapy of Solid Tumor

Journal of Isotopes, 2017
Three aspects of the application of PET/CT in solid tumor chemotherapy were summarized, including the selection of evaluation criteria, the proper time of using PET/CT in the evaluation and the parameters of PET/CT in evaluating the response of ...
positron emission tomography solid tumor chemotherapy predicton of therapeutic response
doaj   +1 more source

Direct contact between Plasmodium falciparum and human B-cells in a novel co-culture increases parasite growth and affects B-cell growth

Malaria Journal, 2021
Background Plasmodium falciparum parasites cause malaria and co-exist in humans together with B-cells for long periods of time. Immunity is only achieved after repeated exposure.
Sreenivasulu B. Reddy, Noemi Nagy, Caroline Rönnberg, Francesca Chiodi, Allan Lugaajju, Frank Heuts, Laszlo Szekely, Mats Wahlgren, Kristina E. M. Persson   +8 more
doaj   +1 more source

The human tumor microbiome is composed of tumor type–specific intracellular bacteria

Science, 2020
Profiling tumor bacteria Bacteria are well-known residents in human tumors, but whether their presence is advantageous to the tumors or to the bacteria themselves has been unclear.
D. Nejman, Ilana Livyatan, Garold Fuks, N. Gavert, Yaara Zwang, L. Geller, Aviva Rotter-Maskowitz, Roi Weiser, Giuseppe Mallel, Elinor Gigi, A. Meltser, G. Douglas, I. Kamer, V. Gopalakrishnan, T. Dadosh, S. Levin-Zaidman, S. Avnet, Tehila Atlan, Z. Cooper, R. Arora, Alexandria P. Cogdill, M. A. W. Khan, G. Ologun, Yuval Bussi, A. Weinberger, M. Lotan-Pompan, O. Golani, G. Perry, Merav Rokah, K. Bahar-Shany, E. Rozeman, C. Blank, Anat Ronai, R. Shaoul, A. Amit, Tatiana Dorfman, R. Kremer, Z. Cohen, S. Harnof, T. Siegal, E. Yehuda‐Shnaidman, E. Gal-Yam, H. Shapira, N. Baldini, M. Langille, A. Ben-nun, B. Kaufman, A. Nissan, T. Golan, M. Dadiani, Keren Levanon, J. Bar, S. Yust-Katz, I. Barshack, D. Peeper, D. Raz, E. Segal, J. Wargo, J. Sandbank, N. Shental, R. Straussman   +60 more
semanticscholar   +1 more source