Results 71 to 80 of about 8,258,963 (388)

Prognostic significance of primary-tumor extension, stage and grade of nuclear differentiation in patients with renal cell carcinoma [PDF]

, 2002
Surgery remains the preferred therapy for renal cell carcinoma. The various adjunctive or complementary therapies currently yield disappointing results. Identifying reliable prognostic factors could help in selecting patients most likely to benefit from ...
Barbarosos A, Bolognese A., Bononi M, D'Andrea N, De Cesare A, FIORE, ELEONORA, Galati G, Izzo L   +7 more
core  

Surgical treatment of benign osteolytic lesions in the femoral head and neck: a systematic review

BMC Musculoskeletal Disorders, 2021
Background and objectives Treatment of benign osteolytic lesions in the femoral head and neck can be extremely challenging, particularly in children with open physis or for aggressive tumors with pathological fracture.
Jingtian Shi, Zhiqing Zhao, Taiqiang Yan, Wei Guo, Rongli Yang, Xiaodong Tang, Huayi Qu, Sen Dong   +7 more
doaj   +1 more source

Molecular subtypes of osteosarcoma classified by cancer stem cell related genes define immunological cell infiltration and patient survival

Frontiers in Immunology, 2022
Recent studies have shown that tumor stemness has biological significance in tumorigenicity and tumor progression. However, the characteristics of TME immune infiltration in osteosarcoma mediated by the combined effects of multiple cancer stem cell ...
Lei Guo, Lei Guo, Taiqiang Yan, Taiqiang Yan, Wei Guo, Wei Guo, Jianfang Niu, Jianfang Niu, Wei Wang, Wei Wang, Tingting Ren, Tingting Ren, Yi Huang, Yi Huang, Jiuhui Xu, Jiuhui Xu, Boyang Wang, Boyang Wang   +17 more
doaj   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Comprehensive analysis of normal adjacent to tumor transcriptomes. [PDF]

, 2017
Histologically normal tissue adjacent to the tumor (NAT) is commonly used as a control in cancer studies. However, little is known about the transcriptomic profile of NAT, how it is influenced by the tumor, and how the profile compares with non-tumor ...
Aran, Dvir, Butte, Atul J, Camarda, Roman, Goga, Andrei, Krings, Gregor, Odegaard, Justin, Oskotsky, Boris, Paik, Hyojung, Sirota, Marina   +8 more
core   +3 more sources

Glucose-activatable insulin delivery with charge-conversional polyelectrolyte multilayers for diabetes care

Frontiers in Bioengineering and Biotechnology, 2022
One of the most effective treatments for diabetes is to design a glucose-regulated insulin (INS) delivery system that could adjust the INS release time and rate to reduce diabetes-related complications.
Yanguang Yang, Xiangqian Wang, Xiaopeng Yuan, Qiwei Zhu, Shusen Chen, Donglin Xia   +5 more
doaj   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

FEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke, Izadora Volpato Rossi, Marcel I. Ramirez   +2 more
wiley   +1 more source

Pathologic evaluation of tumor-associated macrophage density and vessel inflammation in invasive breast carcinomas [PDF]

, 2017
Tumor-associated macrophages (TAMs) are major constituents of the tumor microenvironment in solid tumors and have been implicated as mediators of tumor progression, invasion and metastasis.
Adhikari, Smita, Chervoneva, Inna, Hasan, Nafis, Leslie, Macall, Morita, Yoshihiro, Rui, Hallgeir, Tanaka, Takemi, Zhang, Roy   +7 more
core   +2 more sources

H-DenseUNet: Hybrid Densely Connected UNet for Liver and Tumor Segmentation From CT Volumes

IEEE Transactions on Medical Imaging, 2018
Liver cancer is one of the leading causes of cancer death. To assist doctors in hepatocellular carcinoma diagnosis and treatment planning, an accurate and automatic liver and tumor segmentation method is highly demanded in the clinical practice. Recently,
X. Li, Hao Chen, Xiaojuan Qi, Q. Dou, Chi-Wing Fu, P. Heng   +5 more
semanticscholar   +1 more source

Thrombus or Tumor ?

Clinical Case Reports, 2023
Key clinical messageContrast defects in veins are often diagnosed as benign thrombi, but depending on the patient’s background it is necessary to differentiate between tumor thrombi. It is difficult to differentiate between these using contrast‐enhanced CT alone, but with angioscopy it is easy to visually distinguish between a benign and tumor thrombi ...
Shiho Wakasa, Hiroya Hayashi, Takanori Yamazaki, Yasuhiro Izumiya, Daiju Fukuda   +4 more
openaire   +3 more sources