Results 161 to 170 of about 68,638 (278)

Tumor budding – prognostischer Faktor bei Speicheldrüsenkarzinomen?

Laryngo-Rhino-Otologie, 2020
C Becker, T Villing, T Schulz, G Kayser
openaire   +1 more source

Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases

Journal of Gastroenterology and Hepatology, EarlyView.
Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li, Jia Li, Robin P. F. Dullaart, Han Moshage   +3 more
wiley   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Hydrogels in Periodontal and Craniofacial Regeneration: Current Applications and Next‐Generation Biomaterials

Journal of Periodontal Research, EarlyView.
Hydrogel‐based therapies have proven to be valuable tools to address the unique regeneration challenges of complex multi‐domain periodontal and craniofacial tissues. This review highlights and classifies clinically approved and emerging hydrogel therapies indicated for the regeneration of periodontal and craniofacial tissues.
Z. Gouveia, M. Diba, B. T. Yilmaz, Jae‐Kook Cha, D. T. Wu, D. J. Mooney   +5 more
wiley   +1 more source

The Role of Wnt Signaling in Age‐Related Alveolar Bone Loss and Regeneration

Journal of Periodontal Research, EarlyView.
The graphical abstract summarizes key signaling pathways involved in bone formation and resorption associated with Wnt signaling across young and aged long bone and jaw tissues. Levels of evidence are indicated as robust, moderate, or emerging, reflecting the current experimental support in each context.
Hsiao H. Sung, Navya Chalamalasetty, Ali Alzainal, Hanlong Liu, Lexuan Wang, Pietra Colacrai Arikita, Ivy C. X. Wei, Hom‐Lay Wang, M. H. J. van den Bosch, Michelle S. Caird, Peter M. van der Kraan, Kenneth M. Kozloff, Esmeralda Blaney Davidson   +12 more
wiley   +1 more source

Plant Lipid Droplets and Derived Lipidic Nano‐Assemblies: Structure, Biogenesis and Pharmaceutical Applications

Plant Biotechnology Journal, EarlyView.
ABSTRACT Lipid droplets (LDs) serve as the primary storage site for neutral lipids in plant cells, with growing evidence supporting many additional biological roles, such as in lipid homeostasis, signalling, trafficking, inflammatory responses and inter‐organelle communication.
Abdulsamie Hanano, Amal Yousfan, Denis J. Murphy   +2 more
wiley   +1 more source

Prognostic factors and long‐term outcomes with endoscopic submucosal dissection for colorectal tumors in patients aged 75 years or older

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Background Studies regarding the long‐term outcomes of endoscopic submucosal dissection (ESD) performed in older patients with colorectal tumors are limited. Therefore, in this study, we aimed to analyze the long‐term outcomes of older patients with colorectal tumors who underwent ESD and identify prognostic factors.
Takaya Miura, Satohiro Matsumoto, Azumi Sato, Shu Kojima, Goya Sasaki, Mina Morino, Keita Matsumoto, Hitomi Kashima, Yudai Koito, Takehiro Ishii, Shuhei Yoshikawa, Haruka Otake, Takeshi Uehara, Masanari Sekine, Takeharu Asano, Hiroyuki Miyatani, Hirosato Mashima   +16 more
wiley   +1 more source

Tumor budding in gastric adenocarcinoma: prognostic value and association with clinicopathological markers. [PDF]

Arq Bras Cir Dig
Bacha D, Kammoun N, Troudi B, Attia M, Lahmar-Boufaroua A, Ben-Slama S.   +5 more
europepmc   +1 more source

Feasibility of a novel slim gastroscope for endoscopic submucosal dissection: A case series (with video)

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Endoscopic submucosal dissection has transformed early‐stage gastrointestinal tumor treatment. This series showcases a novel slim gastroscope's efficacy in tackling challenging lesions. Retrospective analysis of 17 patients undergoing endoscopic submucosal dissection using the novel slim gastroscope for pharyngeal, esophageal, gastric ...
Marina Kim, Yohei Minato, Darshan Parekh, Hideyuki Chiba, Ryoju Negishi, Shunya Takayanagi, Kohei Ono, Yuki Kano, Yoshiaki Kimoto, Nao Takeuchi, Shinya Nagae, Ken Ohata   +11 more
wiley   +1 more source