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Prognostic significance of tumor budding in melanoma
Melanoma Research, 2022Cutaneous melanoma is an aggressive neoplasm with growing incidence and continuous research is undertaken for novel prognostic factors. This current research aims to determine if tumor budding is an independent factor that correlates with the survival of patients with melanoma. A total of 742 cases of melanoma were evaluated. A receiver operating curve
Leonardo S, Lino-Silva +4 more
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Tumor Budding Assessment in Colorectal Carcinoma
American Journal of Surgical Pathology, 2023Tumor budding (TB) is a powerful prognostic factor in colorectal cancer (CRC). An internationally standardized method for its assessment (International Tumor Budding Consensus Conference [ITBCC] method) has been adopted by most CRC pathology protocols. This method requires that TB counts are reported by field area (0.785 mm2) rather than objective lens
David P, Cyr +13 more
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Prognostic significance of tumor budding in gastrointestinal tumors
Expert Review of Anticancer Therapy, 2011Tumor budding describes the presence of single tumor cells or small tumor cell clusters at the invasion front of carcinomas. It is currently thought to be the result of epithelial-mesenchymal transformation. Tumor budding can be appreciated histologically during routine evaluation of malignant polyps or surgical specimens of malignant tumors.
Märkl, Bruno, Arnholdt, Hans M.
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Virchows Archiv, 2021
Tumor budding (TB), a histopathological manifestation of epithelial-mesenchymal transition, is an important step in cancer invasion and metastasis development. TB has been considered a strong prognostic indicator in colorectal cancer. The International Tumor Budding Consensus Conference (ITBCC) scoring system is the standardized method used for patient
Han-Na Kim +5 more
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Tumor budding (TB), a histopathological manifestation of epithelial-mesenchymal transition, is an important step in cancer invasion and metastasis development. TB has been considered a strong prognostic indicator in colorectal cancer. The International Tumor Budding Consensus Conference (ITBCC) scoring system is the standardized method used for patient
Han-Na Kim +5 more
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Tumor Budding in Intrahepatic Cholangiocarcinoma
American Journal of Surgical Pathology, 2019Intrahepatic cholangiocarcinoma (ICC) is an extremely aggressive carcinoma. Useful predictors for the patients’ prognosis after surgery have not been fully established. From the University of Tokyo Hospital pathology archives, we reviewed 107 cases of ICC, 54 cases of perihilar cholangiocarcinoma, and 40 cases of extrahepatic cholangiocarcinoma (ECC ...
Mariko, Tanaka +12 more
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American Journal of Surgical Pathology
The mechanism of tumor budding (TB) in gastric adenocarcinoma (GAC) and its relationship with biological indicators and prognostic significance, remains unclear. In this study, we conducted a comprehensive analysis using whole-slide imaging to evaluate TB in 75 cases of GAC.
Jie Lian +6 more
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The mechanism of tumor budding (TB) in gastric adenocarcinoma (GAC) and its relationship with biological indicators and prognostic significance, remains unclear. In this study, we conducted a comprehensive analysis using whole-slide imaging to evaluate TB in 75 cases of GAC.
Jie Lian +6 more
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Prognostic significance of tumor budding in biliary tract cancer
European Journal of Surgical Oncology, 2022Tumor budding is a significant prognostic indicator for poor survival of several solid tumors. However, due to the lack of a standard scoring system, its clinical application for biliary tract cancer (BTC) is limited.To identify the prognostic significance of tumor budding in BTC.Tumor budding was associated with poor histologic differentiation ...
Parbatraj Regmi +7 more
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Three‐dimensional analysis of extrahepatic cholangiocarcinoma and tumor budding
The Journal of Pathology, 2020AbstractAdvances in tissue clearing and microscopy make it possible to study human diseases in three dimensions (3D). High‐grade tumor budding is known to be associated with poor prognosis in various cancers; however, little is known about the 3D architecture of tumor budding.
Tadashi Yoshizawa +9 more
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Tumor budding as a prognostic marker in laryngeal carcinoma
Pathology - Research and Practice, 2010Tumor budding is recognized as an adverse prognostic factor for a few carcinoma types. We evaluated the importance of this finding in 64 laryngeal carcinoma patients treated with surgery and radiotheraphy, with a median follow up of 53 (6-181) months. Budding was determined by re-evaluating hematoxylin-eosin (H&E) stained tumor sections, and classified
SARIOĞLU, SÜLEN +7 more
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