Inflammation is a key contributor to ovarian cancer cell seeding. [PDF]
, 2018 The incidence of ovarian cancer dramatically increases in early menopause but the factors contributing to cancer onset are unclear. Most ovarian cancers originate in the fallopian tube with subsequent implantation of malignant cells into the ovary ...
Jia, Dongyu +3 more
core +1 more source
Late pulmonary metastases of renal cell carcinoma immediately after post-transplantation immunosuppressive treatment: a case report [PDF]
, 2008 Introduction We report a case of pulmonary metastatic recurrence of renal adenocarcinoma soon after radical nephrectomy that was followed by renal transplant and immunosuppressive medication.
Jose Manuel Cozar +4 more
core +1 more source
The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source
Engaging the Immune Response to Normalize the Tumor Microenvironment [PDF]
, 2013 Solid tumors exist as heterogeneous populations comprised not only of malignant cells, but various other cell types, including cells that make up the vasculature, that can strongly influence tumorgenicity.
Sabins, Nina, Storkus, Walter
core
Macrophage phenotypic subtypes diametrically regulate epithelial-mesenchymal plasticity in breast cancer cells [PDF]
, 2016 Background: Metastatic progression of breast cancer involves phenotypic plasticity of the carcinoma cells moving between epithelial and mesenchymal behaviors.
Clark, AM +4 more
core +3 more sources
Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang +7 more
wiley +1 more source
Chemotherapy-induced PTEN-L secretion promotes the selection of PTEN-deficient tumor cells
Journal of Experimental & Clinical Cancer ResearchBackground PTEN loss has been identified in various tumor types and is linked to unfavorable clinical outcomes. In addition to PTEN mutation, multiple mechanisms contribute to PTEN loss during tumor development.
Ming Wang +11 more
doaj +1 more source
A Mathematical Tumor Model with Immune Resistance and Drug Therapy: An Optimal Control Approach [PDF]
, 2001 We present a competition model of cancer tumor growth that includes both the immune system response and drug therapy. This is a four-population model that includes tumor cells, host cells, immune cells, and drug interaction.
de Pillis, Lisette G, Radunskaya, Ami E
core +5 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu +5 more
wiley +1 more source
Mediating the death of dormant tumor cells
Molecular & Cellular Oncology, 2018 How immunological cues trigger cancer cell-intrinsic signaling pathways for their entering dormancy remains an enigma. In out recent studies, we found that IFN-β induces tumor-repopulating cells (TRC) into dormancy by activating Indoleamine-pyrrole 2,3 ...
Yuying Liu, Jiadi Lv, Bo Huang
doaj +1 more source