Results 11 to 20 of about 280,511 (259)

Imaging in Tumor Immunology. [PDF]

open access: yesNucl Med Mol Imaging, 2021
Recent advances in immune modulation have made impressive progress in cancer immunotherapy. Because dynamic nature of the immune response often makes it difficult to evaluate therapeutic outcomes, innovative imaging technologies have been developed to enable non-invasive visualization of immune cells and tumors in their microenvironment.
Kim EE, Youn H, Kang KW.
europepmc   +3 more sources

Mesenchymal stem cell therapy for liver disease: full of chances and challenges

open access: yesCell & Bioscience, 2020
Liver disease is a major health problem that endangers human health worldwide. Currently, whole organ allograft transplantation is the gold standard for the treatment of end-stage liver disease.
Xue Yang   +5 more
doaj   +1 more source

Transcription factors in fibroblast plasticity and CAF heterogeneity

open access: yesJournal of Experimental & Clinical Cancer Research, 2023
In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for more effective therapeutic targeting of pro ...
Roberta Melchionna   +4 more
doaj   +1 more source

Modulation of SLFN11 induces changes in DNA Damage response in breast cancer

open access: yesCancer Cell International, 2023
Background Lack of Schlafen family member 11 (SLFN11) expression has been recently identified as a dominant genomic determinant of response to DNA damaging agents in numerous cancer types.
Christophe Michel Raynaud   +13 more
doaj   +1 more source

A review on tumor immunology

open access: yesJournal of Orofacial Sciences, 2017
The ability of immune system to detect and destroy the altered/abnormal cells may inhibit the development of various cancers. The immune system had been proposed as a tactic in sustaining nonneoplastic state and also for the development of immunotherapy ...
Sri Lalitha Kaja   +5 more
doaj   +1 more source

Isolation of Mononuclear Cell Populations from Ovarian Carcinoma Ascites

open access: yesBio-Protocol, 2017
Ovarian cancer is one of the most fatal tumors in women. Due to a lack of symptoms and adequate screening methods, patients are diagnosed at advanced stages with extensive tumor burden (Jelovac and Armstrong, 2011).
Christina Wefers   +6 more
doaj   +1 more source

Tumor-associated macrophages promote intratumoral conversion of conventional CD4+ T cells into regulatory T cells via PD-1 signalling

open access: yesOncoImmunology, 2022
While regulatory T cells (Tregs) and macrophages have been recognized as key orchestrators of cancer-associated immunosuppression, their cellular crosstalk within tumors has been poorly characterized.
Kevin Kos   +11 more
doaj   +1 more source

Immunologic Treatment of Tumors.

open access: yesExperimental Biology and Medicine, 1959
SummaryWe produced antibodies by injecting cancer cells obtained from Walker 256 tumor into rabbits; after several injections of the cell antigen, the rabbits were exsanguinated, and the serum fractionated. Antibodies to normal tissue were adsorbed out by exposure to normal tissue.
J A, McCREDIE, E R, BROWN, W H, COLE
openaire   +2 more sources

CART cells are prone to Fas- and DR5-mediated cell death

open access: yesJournal for ImmunoTherapy of Cancer, 2018
Adoptive transfer of T cells transduced with Chimeric Antigen Receptors (CAR) are now FDA-approved for the treatment of B-cell malignancies. Yet, the functionality of the endogenous TCR in CART cells has not been fully assessed. Here, we demonstrate that
Benjamin O. Tschumi   +7 more
doaj   +1 more source

Isolation of native EVs from primary biofluids—Free‐flow electrophoresis as a novel approach to purify ascites‐derived EVs

open access: yesJournal of Extracellular Biology, 2022
Although extracellular vesicles (EVs) have been extensively characterized, efficient purification methods, especially from primary biofluids, remain challenging. Here we introduce free‐flow electrophoresis (FFE) as a novel approach for purifying EVs from
Christian Preußer   +11 more
doaj   +1 more source

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