Results 251 to 260 of about 408,319 (335)

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

open access: yesAdvanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao   +17 more
wiley   +1 more source

Tumor immunology and immunotherapy for endometrial cancer

open access: hybrid
Kosuke Murakami   +3 more
openalex   +1 more source

Maximizing Efficacy of Cancer Nanovaccines and Immune Cells Landscape in Responders and Non‐Responders to Immunotherapy

open access: yesAdvanced Science, EarlyView.
To maximize the efficacy of cancer vaccines, adjuvants, collection, lysis, purification, oxidation, loading sites, and sizes, etc., are investigated. The optimized cancer nanovaccines loading whole tumor antigens can cure all or most tumor‐bearing mice in multiple mouse cancer models.
Xiangxiang Xu   +13 more
wiley   +1 more source

From Tumor Immunology to Immunotherapy in Gastric and Esophageal Cancer. [PDF]

open access: yesInt J Mol Sci, 2018
Vrána D   +8 more
europepmc   +1 more source

Tumor glyco-immunology, glyco-immune checkpoints and immunotherapy

open access: gold
Salomé S. Pinho   +2 more
openalex   +1 more source

Localized Delivery of the mRNAs Encoding CD47 Inhibitor and Interleukins 12, 15, and 21 Elicits Robust Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
The co‐delivery of mRNAs encoding a CD47 inhibitor and a cytokine cocktail (interleukins 12, 15, and 21) via lipid nanoparticles enables effective localized immunotherapy. This strategy not only suppresses tumor progression but also enhances type 1 conventional dendritic cell (cDC1) differentiation and activates CD8+ T cells, thereby inducing robust ...
Tao Jiang   +14 more
wiley   +1 more source

Resident memory T cells, critical components in tumor immunology. [PDF]

open access: yesJ Immunother Cancer, 2018
Mami-Chouaib F   +7 more
europepmc   +1 more source

Label‐Free 3D Photoacoustic Imaging of Tumor Organoids for Volumetric Drug Screening

open access: yesAdvanced Science, EarlyView.
A label‐free organoid photoacoustic imaging (LFOPI) system is developed for precise volumetric drug screening evaluation. As a proof of concept, LFOPI's performance in chemotherapy and immunotherapy drug screening assays are further evaluated. The LFOPI offers unique non‐invasive, label‐free capabilities for tumor organoids, and contributes to the ...
Xiaofei Luo   +18 more
wiley   +1 more source

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