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Immunobiology of solid cancers: cellular and molecular pathways as potential diagnostic and therapeutic targets [PDF]
In the last four decades, tumor immunology has shed light on identity and functions of cells and molecules involved in tumor rejection through the involvement of the immune system [1].
Braicu, E. I.+3 more
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Tumor immunology is undergoing a renaissance due to the recent profound clinical successes of tumor immunotherapy. These advances have coincided with an exponential growth in the development of –omics technologies. Armed with these technologies and their
Nathan E Reticker-Flynn+1 more
doaj +1 more source
Regulation of Tumor Immunity by Tumor/Dendritic Cell Fusions [PDF]
The goal of cancer vaccines is to induce antitumor immunity that ultimately will reduce tumor burden in tumor environment. Several strategies involving dendritic cells- (DCs)- based vaccine incorporating different tumor-associated antigens to induce ...
Gong, Jianlin+10 more
core +11 more sources
Tumor immunology in ovarian cancer [PDF]
Ovarian cancer is the third most common gynecological malignancy worldwide with an overall 5-year survival of only 35%. Considering this poor prognosis, novel therapies to improve outcome for ovarian cancer patients are urgently needed.
Merkus-Brunekreeft, Kim
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IX Forum on Translational Immunology and Cancer Immuno-therapy (FIT Cancer 9)
/INTRODUCTIONTumor immunology and cancer immunotherapy is a growing field, continuously evolving. Different types of immunotherapies have been implemented over last decade in the standard of care across several tumor types.
doaj +1 more source
Mesenchymal stem cell therapy for liver disease: full of chances and challenges
Liver disease is a major health problem that endangers human health worldwide. Currently, whole organ allograft transplantation is the gold standard for the treatment of end-stage liver disease.
Xue Yang+5 more
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Transcription factors in fibroblast plasticity and CAF heterogeneity
In recent years, research focused on the multifaceted landscape and functions of cancer-associated fibroblasts (CAFs) aimed to reveal their heterogeneity and identify commonalities across diverse tumors for more effective therapeutic targeting of pro ...
Roberta Melchionna+4 more
doaj +1 more source
Clonal expansion shapes the human V\u3b41T cell receptor repertoire. [PDF]
Cellular and Molecular Immunology aims to report the dynamic progress being made in China and abroad in immunological research, and welcomes high-quality Research Articles, Reviews and Brief Reports across a broad range of topics including, but not ...
Dieli, F., Meraviglia, S.
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The immune system has effectively evolved to protect the host against foreign invaders, including bacterial, viral, and parasitic infiltrates. Less clear has been the interaction and the protective effects the immune system mounts against its own ...
Rachel L. G. Maus+2 more
semanticscholar +1 more source
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Background Lack of Schlafen family member 11 (SLFN11) expression has been recently identified as a dominant genomic determinant of response to DNA damaging agents in numerous cancer types.
Christophe Michel Raynaud+13 more
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