Results 51 to 60 of about 403,248 (353)
Integrative Pan-Cancer Analysis of RNMT: a Potential Prognostic and Immunological Biomarker [PDF]
arXiv, 2022 Background: RNA guanine-7 methyltransferase (RNMT) is one of the main regulators of N7-methylguanosine, and the deregulation of RNMT correlated with tumor development and immune metabolism. However, the specific function of RNMT in pan-cancer remains unclear.
arxiv
Memory NK cell features exploitable in anticancer immunotherapy [PDF]
, 2019 Besides their innate ability to rapidly produce effector cytokines and kill virus-infected or transformed cells, natural killer (NK) cells display a strong capability to adapt to environmental modifications and to differentiate into long-lived ...
Battella, Simone +5 more
core +2 more sources
OncoImmunology, 2020 Glioma represents a serious health burden in terms of morbidity and mortality. The prognostic significance of the lymphoid and myeloid infiltrates in glioma is not clearly determined.
Eliana Marinari +8 more
doaj +1 more source
Newly developed 3D in vitro models to study tumor–immune interaction
Journal of Experimental & Clinical Cancer Research, 2023 Immunotherapy as a rapidly developing therapeutic approach has revolutionized cancer treatment and revitalized the field of tumor immunology research. 3D in vitro models are emerging as powerful tools considering their feature to maintain tumor cells in ...
Peiyuan Mu +11 more
doaj +1 more source
Immunological ignorance of solid tumors [PDF]
Springer Seminars in Immunopathology, 2005 Many peripheral solid tumors such as sarcomas and carcinomas express tumor-specific antigens that can serve as targets for immune effector T cells. Nevertheless, the immune surveillance against clinically manifest carcinomas and sarcomas seems relatively inefficient.
Adrian F. Ochsenbein +1 more
openaire +4 more sources
Generating counterfactual explanations of tumor spatial proteomes to discover effective strategies for enhancing immune infiltration [PDF]
arXiv, 2022 The tumor microenvironment (TME) significantly impacts cancer prognosis due to its immune composition. While therapies for altering the immune composition, including immunotherapies, have shown exciting results for treating hematological cancers, they are less effective for immunologically-cold, solid tumors.
arxiv
Tumor microenvironment and immunology of cholangiocarcinoma
Hepatoma Research, 2022 Cholangiocarcinoma (CCA), an aggressive tumor originating from both intra- and extra-hepatic biliary cells, represents an unmet need in liver oncology, as treatment remains largely unsatisfactory. A typical feature of CCA is the presence of a complex tumor microenvironment (TME) composed of neoplastic cells, a rich inflammatory infiltrate, and cancer ...
Cadamuro M. +3 more
openaire +2 more sources
Frontiers in Immunology, 2023 The development and differentiation of B cells is intimately linked to cell proliferation and the generation of diverse immunoglobulin gene (Ig) repertoires.
Aldo Spanjaard +12 more
doaj +1 more source
Immunologic Treatment of Tumors.
Experimental Biology and Medicine, 1959 SummaryWe produced antibodies by injecting cancer cells obtained from Walker 256 tumor into rabbits; after several injections of the cell antigen, the rabbits were exsanguinated, and the serum fractionated. Antibodies to normal tissue were adsorbed out by exposure to normal tissue.
Eric R. Brown +2 more
openaire +3 more sources
Sensing Danger: Innate Immunology for Intrusion Detection [PDF]
Information Security Technical Report, 12(4), pp 218-227, 2007, 2008 The immune system provides an ideal metaphor for anomaly detection in general and computer security in particular. Based on this idea, artificial immune systems have been used for a number of years for intrusion detection, unfortunately so far with little success. However, these previous systems were largely based on immunological theory from the 1970s
arxiv +1 more source