Results 251 to 260 of about 343,340 (395)

METTL5 Enables Immune Evasion of Liver Cancer via Chemokine mRNA Translation Regulation

Advanced Science, EarlyView.
METTL5 reshapes the tumor immune microenvironment through ribosome 18S rRNA m6A modification to regulate the translation of chemokine mRNA. Targeting METTL5‐mediated immunosuppression unleashes anti‐tumor immunity and improves the efficacy of anti‐PD‐1 therapy.
Shuang Li, Xiao Zhao, Tongtong Song, Qiaoyi Chen, Yanqing Wu, Yuting Zhang, Jingying Chen, Yifan Wu, Bin Li, Xinyue Zhang, Zihao Dai, Lixia Xu, Yubin Xie, Alfred Sze‐Lok Cheng, Jianping Guo, Ming Kuang, Shuibin Lin, Zhenwei Peng, Sui Peng, Xuezhen Zeng   +19 more
wiley   +1 more source

Correspondence on 'Deep learning-based quantification of tumor-infiltrating lymphocytes as a prognostic indicator in nasopharyngeal carcinoma: multicohort findings'. [PDF]

ESMO Open
Liu X, Zhang B.
europepmc   +1 more source

Tumor-infiltrating lymphocytes in cancer immunotherapy: from chemotactic recruitment to translational modeling [PDF]

Fatjona Kraja, Vladimir Jurišić, Altijana Hromić-Jahjefendić, Nafsika Rossopoulou, Θεοδώρα Κάτσιλα, Katarina Mirjačić Martinović, Javier De Las Rivas, Carmen C. Diaconu, Árpád Szöőr   +8 more
openalex   +1 more source

Supplementary Data from Adoptive Cellular Therapy with Autologous Tumor-Infiltrating Lymphocytes and T-cell Receptor–Engineered T Cells Targeting Common p53 Neoantigens in Human Solid Tumors

, 2023
Sanghyun P. Kim, Nolan R. Vale, Nikolaos Zacharakis, Sri Krishna, Zhiya Yu, Billel Gasmi, Jared J. Gartner, Sivasish Sindiri, Parisa Malekzadeh, Drew C. Deniger, Frank J. Lowery, Maria R. Parkhurst, Lien T. Ngo, Satyajit Ray, Yong F. Li, Victoria Hill, Maria Florentin, Robert V. Masi, Biman C. Paria, Noam Levin, Alakesh Bera, Elizabeth A. Hedges, Agnes Choi, Praveen D. Chatani, Anup Y. Parikh, Shoshana T. Levi, Samantha J. Seitter, Yong‐Chen Lu, Zhili Zheng, Todd D. Prickett, Li Jia, Jonathan M. Hernandez, Chuong D. Hoang, Paul F. Robbins, Stephanie L. Goff, Richard M. Sherry, James C. Yang, Steven A. Rosenberg   +37 more
openalex   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Predictive and prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancer: a real-world study from Vietnam. [PDF]

Ther Adv Med Oncol
Tran LDN, Nguyen KK, Pham TM, Nguyen QH, Thai TA, Phan DTH, Cung ATT.   +6 more
europepmc   +1 more source

Supplementary Table S4 from Tumor-Infiltrating Lymphocytes Refine Outcomes in Triple-Negative Breast Cancer Treated with Anthracycline-Free Neoadjuvant Chemotherapy

Miguel Martín, Rachel Yoder, Roberto Salgado, Marı́a del Monte-Millán, Enrique L. Álvarez, Isabel Echavarría, Joshua M. Staley, Anne O’Dea, Lauren Nye, Shane R. Stecklein, Coralia Bueno, Yolanda Jerez, María Cebollero, Oscar Bueno, José Á. García-Sáenz, Fernando Moreno, Uriel Bohn, Henry Gómez, Tatiana Massarrah, Qamar J. Khan, Andrew K. Godwin, Sara López‐Tarruella, Priyanka Sharma   +22 more
openalex   +1 more source

P12.01 Utilizing radiation to improve adoptive cell therapy with tumor infiltrating lymphocytes [PDF]

Nina Obertopp, Anne Thomas, J. Ali, Jamie Blauvelt, Amy Hall, Heiko Enderling, Shari Pilon‐Thomas   +6 more
openalex   +1 more source

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

Advanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin, Chenchen Zhang, Jiahao Li, Kun Huang, Min Qiu   +4 more
wiley   +1 more source

Response to correspondence on 'Deep learning-based quantification of tumor-infiltrating lymphocytes as a prognostic indicator in nasopharyngeal carcinoma: multicohort findings'. [PDF]

ESMO Open
Lu T, Li J.
europepmc   +1 more source