Results 251 to 260 of about 267,145 (352)

Association of stromal tumor-infiltrating lymphocytes with clinicopathological parameters in endometrial cancer. [PDF]

Korean J Clin Oncol
Ahuja S, Dubey A, Zaheer S.
europepmc   +1 more source

HLA‐DR⁺ Tumor Cells Show an Association with a Distinct Immune Microenvironment and CD8⁺ T‐Cell Exhaustion in HBV‐Associated Hepatocellular Carcinoma

Advanced Science, EarlyView.
This study integrates scRNA‐seq, multiplex immunofluorescence, and clinical data to identify HLA‐DR⁺tumor cells uniquely enriched in Hepatocellular carcinoma (HCC) with hepatitis B virus (HBV). These cells express MHC II, associate with PD‐L1, recruit and exhaust CD8⁺T cells, predict poor survival, and serve as potential biomarkers for immunotherapy ...
Jun‐Qing Chang, Yan Guo, Wen‐Jing Yuan, Yu‐Man Chen, Bo‐Wei Liu, Wen‐Tao Li, Xiang‐Ming Ding, Xu‐Dong Fu, Yu‐Han Lou, Zhuo‐Ran Chen, Xiao‐Ying Luo, Song‐Ze Ding, Bing‐Yong Zhang, Xiu‐Ling Li, Yong‐Zhi Hong, Shun‐Dong Cang, Dong‐Xiao Li, Ling Lan   +17 more
wiley   +1 more source

Tissue-matched analysis of MRI evaluating the tumor infiltrating lymphocytes in hepatocellular carcinoma. [PDF]

Int J Cancer
Huang M, Song C, Zhou X, Wang H, Lin Y, Wang J, Cai H, Wang M, Peng Z, Dong Z, Feng ST.   +10 more
europepmc   +1 more source

Gene Transfer of Tumor-Reactive TCR Confers Both High Avidity and Tumor Reactivity to Nonreactive Peripheral Blood Mononuclear Cells and Tumor-Infiltrating Lymphocytes

, 2006
Laura A. Johnson, Bianca Heemskerk, Daniel J. Powell, Cyrille J. Cohen, Richard A. Morgan, Mark E. Dudley, Paul F. Robbins, Steven A. Rosenberg   +7 more
openalex   +1 more source

Immunophenotyping of Newly Diagnosed and Recurrent Glioblastoma Defines Distinct Immune Exhaustion Profiles in Peripheral and Tumor-infiltrating Lymphocytes

Clinical Cancer Research, 2018
M. Mohme, S. Schliffke, C. Maire, A. Rünger, L. Glau, K. Mende, J. Matschke, C. Gehbauer, N. Akyüz, S. Zapf, Mareike Holz, M. Schaper, Tobias Martens, N. Schmidt, S. Peine, M. Westphal, M. Binder, E. Tolosa, K. Lamszus   +18 more
semanticscholar   +1 more source

Mitochondrial Regulation of CD8⁺ T Cells: Mechanisms and Therapeutic Modulation

Advanced Science, EarlyView.
This article comprehensively explores the pivotal role of mitochondrial function in CD8⁺ T cell immunotherapy. It highlights how mitochondrial dynamics regulate T cell activation, differentiation, and persistence, and how mitochondrial dysfunction leads to immune exhaustion and impaired antitumor/antiviral responses.
Xu Chen, Pei Lin, Ye Lu, Jiarong Zheng, Yunfan Lin, Zihao Zhou, Li Cui, Xinyuan Zhao   +7 more
wiley   +1 more source

Pathological complete response, histologic grade, and level of stromal tumor-infiltrating lymphocytes in ER + HER2- breast cancer. [PDF]

Breast Cancer Res
Baek SH, Lee MJ, Kook Y, Bae SJ, Jeong J, Cha YJ, Ahn SG.   +6 more
europepmc   +1 more source

Inhibition of Human Tumor-Infiltrating Lymphocyte Effector Functions by the Homophilic Carcinoembryonic Cell Adhesion Molecule 1 Interactions

, 2006
Gal Markel, Rachel Seidman, Noam Stern, Tali Cohen-Sinai, Orit Izhaki, Gil Katz, Michal J. Besser, Avraham J. Treves, Richard S. Blumberg, Ron Loewenthal, Ofer Mandelboim, Arie Orenstein, Jacob Schachter   +12 more
openalex   +1 more source

Presence of tertiary lymphoid structures determines the level of tumor-infiltrating lymphocytes in primary breast cancer and metastasis

Modern Pathology, 2018
Miseon Lee, Sun‐Hee Heo, I. Song, Hajar Rajayi, Hye Seon Park, I. Park, Young-Ae Kim, Hee-Seop Lee, G. Gong, H. Lee   +9 more
semanticscholar   +1 more source

Cryogel‐Based Dendritic Cell Immunotherapy for Post‐Surgical Breast Cancer Treatment

Advanced Science, EarlyView.
A multifunctional GelMA cryogel enables dendritic cell immunotherapy that synergizes with doxorubicin and PD‐1 blockade, driving robust post‐surgical T‐cell immunity and suppressing TNBC recurrence. Abstract Triple‐negative breast cancer (TNBC) is an aggressive malignancy with high mortality and limited treatment options.
Lam‐Duc‐Huy Nguyen, Sheng‐Liang Cheng, Yu‐Ting Yen, Hsin‐Mei Lee, Te‐Haw Wu, Jane Wang, Shu‐Yi Lin, Yunching Chen   +7 more
wiley   +1 more source