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Lymphocytic infiltration in murine tumors.
Journal of medicine, 1979Histologic grading of the histiolymphocytic reaction in nodules of T241 or B16 murine tumors in 94 C57BL/6J mice was performed at various time intervals post-inoculation. The infiltrate occurring in the first four days was generally sparse and no significant difference was observed between two different dose control inocula, suggesting a weak primary ...
C P, Karakousis +4 more
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Tumor-Infiltrating Lymphocytes and Their Role in Solid Tumor Progression
2013Tumor-infiltrating lymphocytes (TIL) are an important component of the tumor environment. Their role in tumor growth and progression has been debated for decades. Today, emphasis has shifted to beneficial effects of TIL for the host and to therapies optimizing the benefits by reducing immune suppression in the tumor microenvironment. Evidence indicates
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Multiparametric analysis of tumor infiltrating lymphocytes in solid tumors
The use of single-cell technologies in characterizing the interactions between immune and cancer cells is in continuous expansion. Indeed, the combination of different single-cell approaches enables the definition of novel phenotypic and functional aspects of the immune cells infiltrating the tumor microenvironment (TME). This approach is promoting theBorella R. +8 more
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Tumor-infiltrating lymphocytes: Warriors fight against tumors powerfully
Biomedicine and Pharmacotherapy, 2020Xiao Zhu, Liao Cui, Xiaosong Li
exaly