Results 251 to 260 of about 124,855 (301)

From Marginal to Central: Marginal Zone‐like B Cells as Critical Targets in Cladribine‐Treated Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Multiple sclerosis (MS) is a chronic autoimmune disease where B cells play a central pathogenic role. Cladribine, an oral therapy, provides durable benefits by reshaping lymphocyte populations, yet its specific long‐term impact on distinct B‐cell subsets is not fully understood.
Marta Pirronello, Mario Picozza, Gisella Guerrera, Silvia Corbisiero, Andrea Misiti, Roberta C. Placido, Alice Verdiani, Lorenzo de Marco, Manolo Sambucci, Elena Olivieri, Daniela F. Angelini, Esmeralda Quartuccio, Luca Prosperini, Carla Tortorella, Maria C. Buscarinu, Valeria Zancan, Francesca de Masi, Marco Salvetti, Claudio Gasperini, Giovanna Borsellino, Luca Battistini   +20 more
wiley   +1 more source

Automated quantification of tumor-infiltrating lymphocytes by machine learning reveals prognostic and immunogenomic features in lung cancer. [PDF]

Sci Rep
Li A, Pang Y, Zhang H, Wu D, Lin L, He Z, Liang Z, Chen J, Li F.   +8 more
europepmc   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

A computer vision method to evaluate tumor-infiltrating lymphocytes and multiparametric modeling of neoadjuvant systemic therapy response in breast cancer. [PDF]

Ther Adv Med Oncol
Bielecki M, Lu FI, Vo A, Rakovitch E, Jerzak KJ, Salgado R, Karshafian R, Tran WT.   +7 more
europepmc   +1 more source

Minimally expanded breast cancer tumor-infiltrating-lymphocytes provide guidance for therapeutic selection. [PDF]

Front Immunol
Aran A, Lázaro G, Marco V, Peg V, Faus M, Garrigós L, Pérez-García J, Cortés J, Martí M.   +8 more
europepmc   +1 more source

Phase I trial of locoregional administration of autologous tumor-infiltrating lymphocytes in patients with uveal melanoma and liver metastases (the HAITILS trial). [PDF]

J Immunother Cancer
Nelson A, Riise R, Alsén S, Wong A, Carlson P, Edman S, Holgersson J, Olofsson Bagge R, Johansson I, Sadik M, Edenbrandt L, Nilsson LM, Nilsson JA, Ny L.   +13 more
europepmc   +1 more source

Correction: Lymphocyte activating gene 3 protein expression in nasopharyngeal carcinoma is correlated with programmed cell death-1 and programmed cell death ligand-1, tumor-infiltrating lymphocytes. [PDF]

Cancer Cell Int
Luo F, Cao J, Lu F, Zeng K, Ma W, Huang Y, Zhang L, Zhao H.   +7 more
europepmc   +1 more source

Title: AI-based quantification of tumor-infiltrating lymphocytes with integrative transcriptomics in ovarian clear cell carcinoma: JGOG3025-TR1/A1 study. [PDF]

Cancer Immunol Immunother
Hamada K, Hamanishi J, Ueda A, Takamatsu S, Yoshihara K, Nagasawa T, Seki T, Kikuchi A, Fujimoto E, Taki M, Yamanoi K, Murakami R, Kumada K, Oda K, Shimada M, Okamoto A, Mandai M, Matsumura N.   +17 more
europepmc   +1 more source

Clinical characteristics and prognostic impact of HER2-ultralow breast cancer and tumor-infiltrating lymphocytes (TILs). [PDF]

BMC Cancer
Takada K, Kashiwagi S, Nishikawa M, Kochi A, Watanabe C, Kinoshita H, Ogisawa K, Shibutani M, Morisaki T.   +8 more
europepmc   +1 more source

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Tumor-Infiltrating Lymphocytes

The Cancer Journal, 2015
Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TILs) in combination with lymphodepletion and high-dose interleukin 2 has shown reproducible objective response rates of approximately 50% in patients with highly advanced, refractory metastatic melanoma.
Michal J, Besser, Ronnie, Shapira-Frommer, Jacob, Schachter   +2 more
openaire   +3 more sources