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1. Thomas B. Russell, MD* 2. David E. Kram, MD, MCR* 1. *Section of Pediatric Hematology/Oncology, Department of Pediatrics, Wake Forest School of Medicine, Winston-Salem, NC * AKI: : acute kidney injury ALL: : acute lymphoblastic leukemia HRD: : high-risk disease IRD: : intermediate-risk disease LRD:
Thomas B, Russell, David E, Kram
+9 more sources
Tumor lysis syndrome (TLS) is an acute, life-threatening disease among adults and children that is associated with the initiation of cytoreductive therapy in the treatment of malignancy. A pattern of metabolic derangements occurs as a result of a massive release of intracellular contents into the systemic circulation.
Shelly M, Williams, Anthony A, Killeen
+7 more sources
The Tumor Lysis Syndrome [PDF]
The tumor lysis syndrome is the most common disease-related emergency in children and adults with hematologic cancers. This review summarizes current strategies for risk assessment, prophylaxis, and therapy.
Scott C, Howard +2 more
openaire +6 more sources
Tumor Lysis Syndrome : Correspondence [PDF]
To the Editor:We read with interest the management protocol on Tumor lysis syndrome [1] by Rajendran et al. The guidelines are lucid and will be helpful in managing a common emergency in children with malignancies. However, there are a few points which need clarification: Firstly, what should be the choice of fluid for hyperhydration?
Vineeta, Gupta, Sanjeev Kumar, Gupta
openaire +2 more sources
Tumor Lysis Syndrome in a Low-Risk Pancreatic Cancer Patient
Tumor lysis syndrome (TLS) is the most common hematologic emergency encountered during the treatment of high-grade malignancies. While it can lead to death, the prognosis is typically excellent if caught early on in the course.
Paul Travers +2 more
doaj +1 more source
On the isolation of TI-plasmid from Agrobacterium tumefaciens [PDF]
An efficient lysis method for Agrobacterium cells was developed, which allows a reproducible isolation of the tumor inducing (TI)-plasmid. The lysis method is based on the sensitivity of this bacterium to incubation with lysozyme, n-dodecylamine,EDTA ...
Dons, Johannes JM +7 more
core +2 more sources
Tumor lysis syndrome (TLS) is a potentially life-threatening complication of chemotherapy. It usually occurs in rapidly proliferating hematological malignancies. TLS is deemed spontaneous (STLS) when it occurs prior to any cytotoxic or definite treatment.
Inna Shaforostova +4 more
doaj +1 more source
Background Tumor lysis syndrome is an oncological emergency triggered by the rapid release of intracellular materials from lysed malignant cells. Intensive chemotherapy is challenging for patients with severe renal dysfunction and a high risk of tumor ...
Takahiro Kawaji +8 more
doaj +1 more source
ICAM- melanoma cells are relatively resistant to CD3-mediated T-cell lysis [PDF]
The primary activation pathway of T cells is via the T-cell receptor (TCR)/CD3 complex, which is functionally interrelated with various accessory molecules.
Bolhuis, R.L.H. (Reinder) +5 more
core +1 more source
Consensus conference on the management of tumor lysis syndrome
Tumor lysis syndrome is a potentially life threatening complication of massive cellular lysis in cancers. Identification of high-risk patients and early recognition of the syndrome is crucial in the institution of appropriate treatments.
Patrizia Tosi +10 more
doaj +1 more source

