Results 241 to 250 of about 489,862 (290)

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

open access: yesAdvanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore   +20 more
wiley   +1 more source

Effectiveness of fractionated rituximab in preventing tumor lysis syndrome in aggressive B-cell lymphoma: Insights from real-life clinical practice. [PDF]

open access: yesCancer Rep (Hoboken)
Mohamad J   +8 more
europepmc   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan   +11 more
wiley   +1 more source

Tumor lysis syndrome following letrozole for locally advanced breast cancer: a case report. [PDF]

open access: yesSurg Case Rep
Kikuchi M   +7 more
europepmc   +1 more source

Tumor Lysis Syndrome

Clinical Journal of Oncology Nursing, 2004
Tumor lysis syndrome (TLS) is an oncologic emergency characterized by electrolyte and metabolic disturbances that most commonly are associated with lymphoproliferative malignancies and chemotherapy administration. It is manifested by hyperkalemia, hyperphosphatemia, hypocalcemia, and hyperuricemia.
Diane Cope, Jeannine M. Brant
  +6 more sources

Tumor Lysis Syndrome

Advances in Chronic Kidney Disease, 2021
Tumor lysis syndrome (TLS) is an oncologic emergency due to massive tumor cell lysis with the release of large amounts of potassium, phosphate, and nucleic acids into the systemic circulation. Clinical presentation is characterized by hyperkalemia, hyperphosphatemia, hyperuricemia, and hypocalcemia. Acute kidney injury due to tumor lysis is potentiated
Tarek Barbar, Insara Jaffer Sathick
openaire   +2 more sources

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