Spontaneous Tumor Lysis Syndrome in Diffuse Large B-cell Lymphoma: Early Diagnosis and Management
Cureus, 2019 Spontaneous tumor lysis syndrome is a rare oncological emergency associated with multiorgan failure. It is characterized by an elevation of uric acid, hyperphosphatemia, hypocalcemia, hyperkalemia and renal failure in the setting of no active ...
M. Gangireddy +3 more
semanticscholar +1 more source
The Korean Society for Neuro-Oncology (KSNO) guideline for antiepileptic drug usage of brain tumor: Version 2021.1 [PDF]
, 2021 Background: To date, there has been no practical guidelines for the prescription of antiepileptic drugs (AEDs) in brain tumor patients in Korea. Thus, the Korean Society for Neuro-Oncology (KSNO), a multidisciplinary academic society, had begun preparing
김세훈, 윤홍인, 장종희
core +1 more source
Tumor lysis syndrome in pediatric patients with hematological malignancies
Journal of Applied Hematology, 2022 BACKGROUND: Tumor lysis syndrome (TLS) is a common complication of hematological malignancies and consists of either hyperkalemia, hyperphosphatemia, hyperuricemia, or hypocalcemia. These metabolic derangements may result in clinical tumor lysis syndrome
Lamis Hani Elkhatib +5 more
doaj +1 more source
Prevention and treatment of tumor lysis syndrome, and the efficacy and role of rasburicase
OncoTargets and Therapy, 2017 Tumor lysis syndrome (TLS) is a potentially life-threatening condition that occurs in oncologic and hematologic patients with large tumor burden, either due to cytotoxic therapy or, less commonly, spontaneously because of massive tumor cell lysis. TLS is
N. Alakel +3 more
semanticscholar +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Update on the prevention and treatment of tumor lysis syndrome
Journal of Onco-Nephrology, 2019 Tumor lysis syndrome is a constellation of metabolic derangements seen when tumor cells die and release their intracellular contents into the systemic circulation.
Krishna Sury
semanticscholar +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
A Case Report of Atezolizumab Induced Tumor Lysis Syndrome
The American journal of case reports, 2019 Patient: Female, 67 Final Diagnosis: Atezolizumab induced tumor lysis syndrome Symptoms: Generalized weakness • hematuria • nausea • vomiting Medication: Atezolizumab Clinical Procedure: — Specialty: Oncology Objective: Unusual clinical course Background:
F. Fa'ak, Diego Vanegas, K. Osei
semanticscholar +1 more source
Viral antigen mediated NKp46 activation of NK cells results in tumor rejection via NK-DC crosstalk
, 2012 Natural killer (NK) cells play a critical role in antitumor immunity, their activation being regulated through NK cell receptors. Although the endogenous ligands for these receptors are largely unknown, viral ligands have been identified. We investigated
Bateman, Andrew R +4 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source