Effects of Tributyltin Chloride on Human Neuronal Differentiation and Mice Brain Development
ABSTRACT According to the developmental origins of health and disease hypothesis, perinatal exposure to an environmental toxicant during the development of the nervous system could cause a permanent cellular modification that may promote the appearance of neurodegenerative diseases at an older age.
Ester López‐Gallardo +10 more
wiley +1 more source
Otitis in pet guinea pigs: Causes, clinical signs, treatment and outcomes
Abstract Background Otitis is a major disease impacting both pet guinea pigs and laboratory guinea pigs that are used as models in human otological studies. Methods Medical records from two veterinary clinics were retrospectively reviewed to identify guinea pigs diagnosed with computed tomography (CT)‐confirmed otitis between 2014 and 2023.
Patricia Muffat‐es‐Jacques +5 more
wiley +1 more source
Tumor lysis syndrome: current perspective
Jessica Hochberg, Mitchell S. Cairo
doaj +1 more source
A Rare Case of Spontaneous Tumor Lysis Syndrome in a Pulmonary Neuroendocrine Tumor. [PDF]
Graber JL, Makram M, El Charabaty E.
europepmc +1 more source
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu +10 more
wiley +1 more source
Fatal Tumor Lysis Syndrome Induced by Pembrolizumab in Advanced Renal Pelvis Cancer. [PDF]
Asakura T +3 more
europepmc +1 more source
Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes +2 more
wiley +1 more source
Tumor Lysis Syndrome Induced by Hormonal Therapy in Metastatic Prostate Cancer: A Case Report. [PDF]
Machado M +4 more
europepmc +1 more source
Club Cells in Nasal Epithelial Repair: Insights From an IL‐13‐Induced Inflammatory Model
Four inflammatory endotypes of CRSwNP, defined by eosinophil and neutrophil infiltration, show distinct patterns of basal, club, ciliated, and goblet cell expression in nasal epithelium. Using an ALI‐HNECs model, we demonstrate that IL‐13 impairs mucociliary function by promoting club‐to‐goblet cell differentiation while inhibiting club‐to‐ciliated ...
Zhi‐Qun Huang +13 more
wiley +1 more source
A potential risk factor associated with acute tumor lysis syndrome in dogs with multicentric lymphoma receiving chemotherapy. [PDF]
Yamazaki H +6 more
europepmc +1 more source

