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This simulation case is designed to educate medical students and residents about tumor lysis syndrome. Participants are responsible for caring for a simulated patient with tumor lysis syndrome, whereby they evaluate, diagnose, and treat the critically ...
Jessica Brooks +2 more
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1. Thomas B. Russell, MD* 2. David E. Kram, MD, MCR* 1. *Section of Pediatric Hematology/Oncology, Department of Pediatrics, Wake Forest School of Medicine, Winston-Salem, NC * AKI: : acute kidney injury ALL: : acute lymphoblastic leukemia HRD: : high-risk disease IRD: : intermediate-risk disease LRD:
Thomas B, Russell, David E, Kram
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Tumor lysis syndrome (TLS) is an acute, life-threatening disease among adults and children that is associated with the initiation of cytoreductive therapy in the treatment of malignancy. A pattern of metabolic derangements occurs as a result of a massive release of intracellular contents into the systemic circulation.
Shelly M, Williams, Anthony A, Killeen
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The Tumor Lysis Syndrome [PDF]
The tumor lysis syndrome is the most common disease-related emergency in children and adults with hematologic cancers. This review summarizes current strategies for risk assessment, prophylaxis, and therapy.
Scott C, Howard +2 more
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Tumor Lysis Syndrome : Correspondence [PDF]
To the Editor:We read with interest the management protocol on Tumor lysis syndrome [1] by Rajendran et al. The guidelines are lucid and will be helpful in managing a common emergency in children with malignancies. However, there are a few points which need clarification: Firstly, what should be the choice of fluid for hyperhydration?
Vineeta, Gupta, Sanjeev Kumar, Gupta
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Cisplatin-Based Chemotherapy for Pulmonary Metastasized Germ Cell Tumors of the Testis - Be Aware of Acute Respiratory Distress Syndrome [PDF]
Background: Cisplatin-based combination chemotherapy is regarded as standard of care for patients with advanced germ cell tumors. In patients with lung metastases and a high tumor load, an association between induction chemotherapy and the development of
Baumann, Anja +6 more
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Consensus conference on the management of tumor lysis syndrome
Tumor lysis syndrome is a potentially life threatening complication of massive cellular lysis in cancers. Identification of high-risk patients and early recognition of the syndrome is crucial in the institution of appropriate treatments.
Patrizia Tosi +10 more
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Background Tumor lysis syndrome is an oncologic emergency that involves multiple metabolic abnormalities and clinical symptoms such as acute renal failure, cardiac arrhythmias, seizures, and multiorgan failure, and may be fatal if not promptly recognized.
Steven N. Luminais +5 more
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Urate Nephropathy from Tumor Lysis Syndrome in an Undiagnosed Case of Prostate Cancer
Prostate cancer can masquerade as just normocytic anemia and thrombocytopenia, thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome (HUS), or tumor lysis syndrome (TLS).
Sidra Javed
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Early Investigations and Recent Advances in Intraperitoneal Immunotherapy for Peritoneal Metastasis. [PDF]
Peritoneal metastasis (PM) is an advanced stage malignancy largely refractory to modern therapy. Intraperitoneal (IP) immunotherapy offers a novel approach for the control of regional disease of the peritoneal cavity by breaking immune tolerance.
Bowne, Wilbur B. +5 more
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