Results 281 to 290 of about 154,631 (333)

Enhanced Expression of IL32 mRNA in Skeletal Muscles in the Context of Head and Neck Carcinomas

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Cancer‐related sarcopenia (CRS) is a significant complication of head and neck carcinoma (HNC), characterised by muscle degeneration and poor clinical outcomes. Although various dietary and therapeutic interventions have been explored, most of them remain empirical, and the molecular mechanisms underlying CRS are not yet fully ...
Imane Baïche   +17 more
wiley   +1 more source

Tumor lysis syndrome following letrozole for locally advanced breast cancer: a case report. [PDF]

open access: yesSurg Case Rep
Kikuchi M   +7 more
europepmc   +1 more source

Ellagic Acid Alleviates Abnormal Fat Reduction by Activating the RXRβ–PPARγ Pathways in a CT26 Tumour‐Induced Cachexia Mouse Model

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Cancer cachexia is a syndrome characterized by significant weight loss, particularly of adipose tissue, which negatively impacts patient survival. Pharmacological approaches to prevent this abnormal fat reduction remain poorly defined.
Woo Yong Park   +12 more
wiley   +1 more source

Largely Distinct Post‐Translational Modifications Differentiate Skeletal Muscle Wasting Caused by Cancer, Dexamethasone and Aging

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Skeletal muscle wasting and weakness are prominent disease features. Originally considered to arise from common transcriptional changes, recent analyses demonstrated that different stimuli induce muscle wasting via largely distinct mRNA and protein changes.
Anna Stephan   +6 more
wiley   +1 more source

The Phospholipid Bis(monoacylglycero)Phosphate Confers Antitumour Immunogenicity to Exosomes Secreted by Dendrogenin A, Which Activates Its Biosynthesis in Tumour Cells

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 2, February 2026.
Dendrogenin A stimulates, via LXRβ, the expression and activity of enzymes responsible for the biosynthesis of the phospholipid BMP. BMP is a key determinant of the antitumour immunogenicity of exosomes secreted by DDA‐treated melanoma and triple‐negative breast cancer cells and enhances mouse survival and anti‐PD‐1 therapy in melanoma.
Julio Buñay   +11 more
wiley   +1 more source

Differentiating Damp‐Heat and Cold‐Damp Diarrhea in Rat Models via Gut Microbiota Dysbiosis and Short‐Chain Fatty Acid Profiling

open access: yesMicrobiologyOpen, Volume 15, Issue 1, February 2026.
ABSTRACT On the basis of gut microbiota and short‐chain fatty acids (SCFAs), this study aims to identify diagnostic biomarkers for damp‐heat diarrhea and cold‐damp diarrhea. Rat models of damp‐heat diarrhea and cold‐damp diarrhea were established. Changes in body weight, body temperature, food intake, water consumption, and the diarrhea index were ...
Hao Zhang   +5 more
wiley   +1 more source

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