Results 121 to 130 of about 3,561,070 (402)

Computer simulation of glioma growth and morphology [PDF]

, 2007
Despite major advances in the study of glioma, the quantitative links between intra-tumor molecular/cellular properties, clinically observable properties such as morphology, and critical tumor behaviors such as growth and invasiveness remain unclear ...
Adam, Ambrosi, Ambrosi, Anderson, Anderson, Anderson, Anderson, Araujo, Augustin, Bartels, Bello, Bellomo, Berger, Bernsen, Bernsen, Boegler, Brandt, Bullitt, Byrne, Byrne, Byrne, Byrne, Cai, Carmeliet, Chaplain, Chaplain, Chaplain, Chaplain, Condeelis, Cristini, Cristini, Cursiefen, DeJaeger, Derycke, Eble, Elaine L. Bearer, Ellis, Elvin, Fallenstein, Frieboes, Friedl, Friedl, Friedl, Friedman, Garcke, Gatenby, Giese, Greenspan, Hayot, Helmlinger, Hermann B. Frieboes, Holash, Holash, Huang, Jacqmin, Jain, Jain, John S. Lowengrub, Keller, Khoshyomn, Kim, Kim, Kim, Kopfstein, Kuiper, Kumar, Kunkel, Lah, Lamszus, Lee, Leo, Less, Li, Li, Lockett, Lowengrub, Macklin, Macklin, McDougall, McLean, Naganuma, O'Connor, Ommaya, Padera, Page, Patan, Patan, Paul Macklin, Pennacchietti, Plank, Plank, Preusser, Ridley, Rofstad, Rubenstein, S. Wise, Sahai, Sanga, Seftor, Shweiki, Sierra, Sinek, Skinner, Steeg, Sun, Takano, Toker, Tysnes, Vajkoczy, van Kempen, Vittorio Cristini, Wise, Wolf, Wurzel, X. Zheng, Yamaguchi, Yin, Zheng   +117 more
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

The potential of miR-29 in modulating tumor angiogenesis: a comprehensive review

Discover Oncology
MicroRNAs (miRNAs) are a class of short non-coding RNAs that play a crucial role in the post-transcriptional regulation of gene expression. They are associated with various biological processes related to tumors.
Rui-Ting Zhou, Xiao-Jie Luo, Xiao-Xin-Ran Zhang, Jiang-Feng Wu, Yi-Ran Ni   +4 more
doaj   +1 more source

The Tumor Microenvironment in the Response to Immune Checkpoint Blockade Therapies

Frontiers in Immunology, 2020
Tumor cells constantly interact with their microenvironment, which comprises a variety of immune cells together with endothelial cells and fibroblasts.
F. Petitprez, M. Meylan, A. de Reyniès, C. Sautès-Fridman, W. Fridman   +4 more
semanticscholar   +1 more source

Neurofibromin knockdown in glioma cell lines is associated with changes in cytokine and chemokine secretion in vitro. [PDF]

, 2018
The neurofibromin-1 tumor suppressor gene (NF1) is altered in approximately 20% of sporadic glioblastoma (GBM) cases. NF1 deficient GBM frequently shows a mesenchymal gene expression signature, suggesting a relationship between NF1 status and the tumor ...
Mukherjee, Joydeep, Pieper, Russell O, Wood, Matthew D   +2 more
core   +3 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Melanoma and the tumor microenvironment [PDF]

Current Oncology Reports, 2008
Melanoma arises through the accrual of mutations in genes critical for proliferation and survival. Although melanoma had been traditionally conceptualized as a cell-autonomous event, increasing evidence supports the notion that these tumors are not isolated entities but rather depend, interact with, and react to the adjacent microenvironment.
Meenhard Herlyn, Jessie Villanueva
openaire   +3 more sources

Hyaluronic acid alters vessel behavior in CXCL12-treated HUVECs [PDF]

, 2018
Hyaluronic acid (HA) is a key component of the extracellular matrix known for absorbing water, swelling, and altering solid stress of tumors. HA’s anionic behavior may provide important biochemical effects toward tumor progression as well.
Seibel, Alex J.
core  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Fecal microbiota transplantation for ulcerative colitis: a prospective clinical study

BMC Gastroenterology, 2019
Background Fecal microbiota transplantation may contribute to disease remission in ulcerative colitis; however, the factors that determine the effects of treatment remain unknown. The aim of the present study was to prospectively investigate the clinical
Yan Tian, Yan Zhou, Sisi Huang, Jun Li, Kui Zhao, Xiaohui Li, Xiangchen Wen, Xiao-an Li   +7 more
doaj   +1 more source