Results 181 to 190 of about 652,201 (289)

Correction: CDK4/6 inhibition blocks cancer metastasis through a USP51-ZEB1-dependent deubiquitination mechanism

Signal Transduction and Targeted Therapy
Zhen Zhang, Jianjun Li, Yang Ou, Guang Yang, Kaiyuan Deng, Qiong Wang, Zhaoyang Wang, Wenhao Wang, Quansheng Zhang, Hang Wang, Wei Sun, Peiqing Sun, Shuang Yang   +12 more
doaj   +1 more source

From Barrier to Gateway: Nanomaterials Reshaping the Tumor Microenvironment for Therapy. [PDF]

Int J Nanomedicine
Xie M, Sun W, Hu D, Liu L, Han C, Liu W, Liu L, Bao X, Zhang W, Hao X, Zhou Y.   +10 more
europepmc   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Spatial and phenotypic plasticity of B cells in remodeling the tumor microenvironment. [PDF]

J Immunother Cancer
Gao Y, Peng Y, Chen Y, Zeng S, Shen H, Martin A, Cai C, Han Y.   +7 more
europepmc   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Exosomal miR-451a Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Targeting LPIN1

Cellular Physiology and Biochemistry, 2019
Shaorong Zhao, Jianjun Li, Guomin Zhang, Qiong Wang, Chao Wu, Quansheng Zhang, Hang Wang, Peiqing Sun, Rong Xiang, Shuang Yang   +9 more
doaj   +1 more source

Strategies to target PD-1/PD-L1 in the tumor microenvironment. [PDF]

Cell Oncol (Dordr)
Kui Y, Tong F, Zhang R, Dong X, Wang J.
europepmc   +1 more source

Computational Modeling Meets 3D Bioprinting: Emerging Synergies in Cardiovascular Disease Modeling

Advanced Healthcare Materials, EarlyView.
Emerging advances in three‐dimensional bioprinting and computational modeling are reshaping cardiovascular (CV) research by enabling more realistic, patient‐specific tissue platforms. This review surveys cutting‐edge approaches that merge biomimetic CV constructs with computational simulations to overcome the limitations of traditional models, improve ...
Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L. Tomov, Emilio A. Mendiola, Vahid Serpooshan, Reza Avazmohammadi   +7 more
wiley   +1 more source

EMILIN-1 in the tumor microenvironment: insights from CNS tumors and beyond. [PDF]

Front Oncol
Arsentiev KA, Fajardo A, Yuzhalin AE.
europepmc   +1 more source

Microfluidic Modeling of Macrophage‐Induced Cardiac Inflammation Using NF‐κB Reporter Cardiomyocytes

Advanced Healthcare Materials, EarlyView.
A cardiac inflammation model was developed to enable real‐time analysis of macrophage‐cardiomyocyte interactions using NF‐κB‐reporter cardiomyocytes and a microfluidic co‐culture system. A MATLAB‐based model was implemented to optimize cell density and medium resupply based on TNFα diffusion kinetics. Activation thresholds and stress responses in NF‐κB‐
Chao Liu, Xi Rui Qiang Lu, Seoyoung Jeong, Douglas H. Wu, Rodrigo A. Somoza, Parameswaran Ramakrishnan, Samuel E. Senyo   +6 more
wiley   +1 more source