Results 241 to 250 of about 3,620,379 (402)

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

Immunosuppressive Tumor Microenvironment of Osteosarcoma. [PDF]

Cancers (Basel)
Taylor AM, Sheng J, Ng PKS, Harder JM, Kumar P, Ahn JY, Cao Y, Dzis AM, Jillette NL, Goodspeed A, Bodlak A, Wu Q, Isakoff MS, George J, Grassmann JDS, Luo D, Flynn WF, Courtois ET, Robson P, Hayashi M, Paolillo AT, Petrilli AS, Caminada de Toledo SR, Balarezo FS, Lindsay AD, Hoang B, Wong STC, Lau CC.   +27 more
europepmc   +1 more source

Milk Fat Globule EGF-8 Promotes Melanoma Progression through Coordinated Akt and Twist Signaling in the Tumor Microenvironment [PDF]

, 2008
Masahisa Jinushi, Yukoh Nakazaki, Daniel R. Carrasco, Dobrin Draganov, Nicholas Souders, Matthew Johnson, Martín C. Mihm, Glenn Dranoff   +7 more
openalex   +1 more source

Self‐Cascade Catalytic Reaction–Assisted Apoptosis/Calcicoptosis/Ferroptosis Induction with Microsphere‐Aggregated Hydrogels in Triple‐Negative Breast Cancer Therapy

Advanced Functional Materials, EarlyView.
Hyaluronic acid‐dopamine‐based intra‐crosslinked microsphere including cisplatin (HPC MS) is fabricated by spray‐drying and calcium/iron ions are introduced for interparticle crosslinking. Designed microsphere‐aggregated hydrogel (MAH) system including cisplatin/CaO2/FeSO4 can provide apoptosis/calcicoptosis/ferroptosis‐mediated chemo/cascade ...
ChaeRim Hwang, Yeoung Eun Choi, Song Yi Lee, Mrinmoy Karmakar, Qiaojun Hao, Junmin Lee, Hyun‐Jong Cho   +6 more
wiley   +1 more source

Oncolytic virotherapy and tumor microenvironment modulation. [PDF]

Clin Exp Med
Rivera-Orellana S, Bautista J, Palacios-Zavala D, Ojeda-Mosquera S, Altamirano-Colina A, Alcocer-Veintimilla M, Parrales-Rosales G, Izquierdo-Condoy JS, Vásconez-González J, Ortiz-Prado E, Muslin C, López-Cortés A.   +11 more
europepmc   +1 more source

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

Advanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou, Lauren Brown, Christopher M. Madl   +2 more
wiley   +1 more source

Deciphering metabolic reprogramming of immune cells within the tumor microenvironment. [PDF]

J Transl Med
Wang Y, Chen W, Wang Z, Cai S, Zhao X, Jin J, Gao T, Qu J.   +7 more
europepmc   +1 more source

Molecular profiling of classical Hodgkin lymphoma tissues uncovers variations in the tumor microenvironment and correlations with EBV infection and outcome [PDF]

, 2008
Bruno Chetaille, François Bertucci, Pascal Finetti, Benjamin Esterni, Aspasia Stamatoullas, Jean Michel Picquenot, M.C. Copin, F. Morschhauser, Olivier Casasnovas, Tony Petrella, Thierry Jo Molina, Anne Vekhoff, Pierre Feugier, Réda Bouabdallah, Daniel Birnbaum, Daniel Olive, Luc Xerri   +16 more
openalex   +1 more source

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

Cell, 2010
K. Kessenbrock, V. Plaks, Z. Werb
semanticscholar   +1 more source

Photothermal Hydrogel with Mn3O4 Nanoparticles Alleviates Intervertebral Disc Degeneration by Scavenging ROS and Regulating Extracellular Matrix Metabolism

Advanced Functional Materials, EarlyView.
The MPTT‐nanozyme‐hydrogel system (Mn3O4@ChS‐HA) provides a multifunctional therapeutic strategy for intervertebral disc degeneration (IVDD), effectively targeting oxidative stress and enhancing AF repair by restoring extracellular matrix (ECM) and redox homeostasis.
Yangyang Chen, Chan Xue, Feifei Ni, Binwu Hu, Miaoheng Yan, He Zhang, Yuxiang Hu, Xiaoyao Peng, Guangfang Li, Yu Han, Hongjian Liu, Zengwu Shao, Qin Wang, Yulong Wei   +13 more
wiley   +1 more source