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Synthetic tumor microenvironments

Nature Methods, 2021
An artificial system models the mechanical properties of the tumor microenvironment in vitro.
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Meningioma Tumor Microenvironment

2020
The tumor microenvironment consists of noncancerous cells, such as immune cells and fibroblasts, and the proteins produced by these cells as well as the extracellular matrix components in the environment around a tumor. Tumor influences the behavior of the cells present in the surrounding environment, while the cells in the tumor microenvironment ...
Sajad, Sahab-Negah, Ali, Gorji
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Sarcoma Tumor Microenvironment

2020
Components of the tumor microenvironment (TME) are known to play an essential role during malignant progression, but often in a context-dependent manner. In bone and soft tissue sarcomas, disease-regulatory activities in the TME remain largely uncharacterized. This chapter introduces the cellular, structural, and chemical composition of the sarcoma TME
Panagiotis, Tsagozis   +7 more
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The tumor microenvironment

Surgical Oncology, 2012
The concept of the tumor microenvironment, developed from Paget's "seed and soil" theory is made up of the cancer cells, the stromal tissue, and the extracellular matrix. In this mini-review, each of the components of this dynamic network will be examined.
Cynthia E, Weber, Paul C, Kuo
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Parathyroid Tumor Microenvironment

2020
Parathyroid tumors are the second most common endocrine neoplasia, and it is almost always associated with hypersecretion of the parathormone (PTH), involved in calcium homeostasis, causing primary hyperparathyroidism (PHPT). Parathyroid neoplasia has a stromal component particularly represented in atypical adenomatous and carcinomatous lesions ...
Verdelli, Chiara   +2 more
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Esophageal Tumor Microenvironment

2020
Treatment options for patients with esophageal cancer are limited and the overall survival is disappointing. While surgical resection remains the only curative treatment option, there is a need for innovative medical therapies to extend patient survival.
Henrik, Nienhüser   +2 more
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Adipose Tumor Microenvironment

2020
The term "adipose tissue" represents a multicellular and multifunctional organ involved in lipid storage, in hormone and temperature regulation, and in the protection of bones and vital organs from impact-based damage. Emerging evidence now suggests a more malignant role of adipose tissue in promoting cancer onset and progression via the release of ...
Abbie, Zewdu   +3 more
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The Tumor Microenvironment

2010
Recent advances in stem cell and developmental neurobiology have uncovered new perspectives from which we investigate various forms of cancer. Specifically, the hypothesis at tumors are comprised of a subpopulation of malignant cells similar to stem cells is of great interest to scientists and clinicians and has been dubbed the cancer stem cell ...
Lissa, Baird, Alexey, Terskikh
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