Results 311 to 320 of about 3,570,297 (401)

An unexpected player in organ tropism: aspartate functions as signalling molecule to drive lung metastasis

Signal Transduction and Targeted Therapy
Felix C. E. Vogel, Almut Schulze
doaj   +1 more source

Epigenomic preconditioning of peripheral monocytes determines their transcriptional response to the tumor microenvironment. [PDF]

Genome Med
Kiss M, Halasz L, Hadadi E, Berger WK, Tzerpos P, Poliska S, Kancheva D, Gabriel A, Mora Barthelmess R, Debraekeleer A, Brughmans J, Elkrim Y, Martens L, Saeys Y, Daniel B, Czimmerer Z, Laoui D, Nagy L, Van Ginderachter JA.   +18 more
europepmc   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

Tumor Microenvironment-Responsive Nanoparticles: Promising Cancer PTT Carriers. [PDF]

Int J Nanomedicine
Sun H, Li Y, Xue M, Feng D.
europepmc   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

High-Salt Tumor Microenvironment: Not as Bad as It Sounds, Not as Good as It Seems. [PDF]

Cancers (Basel)
Ali U, Tiriveedhi V.
europepmc   +1 more source

Myeloid‐derived suppressor cells (MDSCs) and tumor‐associated macrophages (TAMs) produce CCL22 which selectively recruits regulatory T‐cells (Tregs) to the tumor microenvironment

, 2008
Adam W. Mailloux, Matthew R. Young
openalex   +1 more source

An Animal‐Free Patient‐Derived Tissue‐Mimetic Biochip Model of the Human Synovial Membrane for Human‐Relevant Osteoarthritis Research

Advanced Healthcare Materials, EarlyView.
Reihs et al. present the development of a humanized, animal‐free synovial membrane model for osteoarthritis. Methods include 3D biochip cultures of human‐primary OA synoviocytes with matrix and serum surrogates. Results show replication of synovial architecture and increased Yap1 expression.
Eva I. Reihs, Alexander Stoegner, Mateo G. Vasconez Martínez, Markus M. Schreiner, Melanie Cezanne, Ruth Gruebl‐Barabas, Bettina Rodriguez‐Molina, Juergen Alphonsus, Silvia Hayer, Richard Lass, Iris Gerner, Florien Jenner, Wolfgang Holnthoner, Stefan Toegel, Peter Ertl, Hans P. Kiener, Reinhard Windhager, Mario Rothbauer   +17 more
wiley   +1 more source

The tumor microenvironment of metastatic osteosarcoma in the human and canine lung. [PDF]

Commun Biol
McGee LE, Pereira JS, McEachron TA, Mazcko C, LeBlanc AK, Beck JA.   +5 more
europepmc   +1 more source