Results 151 to 160 of about 314,005 (303)

Plasma endotoxin and tumor necrosis factor-alpha in the hyperkinetic state of cirrhosis.

, 1995
BACKGROUND/AIMS: The factors which trigger the hyperdynamic circulation in cirrhosis remain poorly defined. Plasma levels of the potent vasodilators endotoxin and tumor necrosis factor-alpha may be elevated in patients with cirrhosis, and therefore the ...
Sogni, P, Moreau, R., Soupison, T, Hadengue, A, Goldman, Michel, Le Moine, Olivier, Lebrec, D, Devière, Jacques, Marchant, Arnaud   +8 more
core  

Characteristics of eligible studies utilizing tumor necrosis factor-alpha inhibitors for the cicatricial alopecia treatment.

Characteristics of eligible studies utilizing tumor necrosis factor-alpha inhibitors for the cicatricial alopecia treatment.
Azadeh Goodarzi (3433010), Sara Sadeghi (14319696), Nima Hajizadeh (17941317), Amirhossein Heidari (17941320)   +3 more
core   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Live attenuated varicella vaccines in patients treated with tumor necrosis factor-alpha inhibitors: A clinical trial. [PDF]

Medicine (Baltimore)
Kamei K, Ogura M, Takeuchi I, Shimizu H, Arai K, Shoji K, Kawai T, Miyairi I, Murashima A, Ogimi C.   +9 more
europepmc   +1 more source

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat

, 2007
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury.
Estrada, Eduardo, Candelario-Jalil, Dr. Eduardo, Taheri, Dr. Saeid, Fiebich, Dr. Bernd L., Yang, Dr. Yi, Grossetete, Dr. Mark, Sood, Dr. Rohit, Rosenberg, Dr. Gary A.   +7 more
core  

Tumor necrosis factor alpha inhibition improves fetal growth in a rat model of preeclampsia. [PDF]

Placenta
Coats LE, Campbell N, Solise D, Chamoun GM, Rawls AZ, Demesa A, Turner T, Zheng B, Alexander BT, LaMarca B.   +9 more
europepmc   +1 more source

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Absolute quantification of tumor necrosis factor-alpha by isotope dilution mass spectrometry. [PDF]

Front Chem
Bao C, Wang J, Xia W, Yang K, Shi X, Yang X, Li H, Wang Y, Zhang Y.   +8 more
europepmc   +1 more source

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu, Ming Yi, Ji Chen, Zeda Zhao, Ruocen Liao, Yingnan Wang, Shengtao Hu, Jun Ding, Ronghua Zhao, William Jia, Yinan Shen, Yongchang Wei, Kongming Wu, Zhijun Dai   +13 more
wiley   +1 more source