Results 151 to 160 of about 6,121,735 (304)

Live attenuated varicella vaccines in patients treated with tumor necrosis factor-alpha inhibitors: A clinical trial. [PDF]

Medicine (Baltimore)
Kamei K, Ogura M, Takeuchi I, Shimizu H, Arai K, Shoji K, Kawai T, Miyairi I, Murashima A, Ogimi C.   +9 more
europepmc   +1 more source

Microglial Deubiquitinase OTUD7B Stabilizes STAT3 to Promote Neuroinflammation and Cognitive Decline in Alzheimer's Disease

Advanced Science, EarlyView.
. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li, Hao Tang, Qin Yu, Yuyang Zhang, Binglu Shi, Ying Kong, Leiyu Xu, Jingjing Shao, Chenghong Hu, Lingyu She, Zhe Wang, Haiyi Chen, Aleksandr V. Samorodov, Gang Cao, Xia Zhao, Yi Wang   +15 more
wiley   +1 more source

Polymorphism of the tumor necrosis factor region in relation to disease [PDF]

, 1992
Linden, Sjef M. van der, Messer, Gerald, Kijlstra, Aize, Weiss, Elisabeth H., Verjans, Georges M.   +4 more
core   +1 more source

The effect of anti-tumor necrosis factor-alpha and nonsurgical periodontal therapy in individuals with rheumatoid arthritis. [PDF]

BMC Oral Health
Yemenoglu H, Beder M, Cüre O, Cüre O, Köse O, Arpa M, Atak M, Bostan SA.   +7 more
europepmc   +1 more source

Radiotherapy Enhances the Oncolytic Efficacy of the Novel Oncolytic Herpesvirus VG161 and Amplifies Its Antitumor Immunity in Breast Cancer

Advanced Science, EarlyView.
RT promotes VG161 replication in BC and its immunostimulatory transgenes expression, which is mediated by the upregulation of GADD34 and HVEM caused by RT. The combination therapy with VG161 and RT increases the abundances of tumor‐infiltrating lymphocytes and elicits potent systemic antitumor immunity, thereby effectively inhibiting local tumors and ...
Lijuan Lyu, Ming Yi, Ji Chen, Zeda Zhao, Ruocen Liao, Yingnan Wang, Shengtao Hu, Jun Ding, Ronghua Zhao, William Jia, Yinan Shen, Yongchang Wei, Kongming Wu, Zhijun Dai   +13 more
wiley   +1 more source

Differential effects of splice variants of human IG20 on tumor necrosis factor-alpha-induced apoptosis.

, 2002
Differential effects of splice variants of human IG20 on tumor necrosis factor-alpha-induced ...
Adeeb Mohammad. Al-Zoubi (7966496)
core   +1 more source

Tumor necrosis factor alpha inhibition improves fetal growth in a rat model of preeclampsia. [PDF]

Placenta
Coats LE, Campbell N, Solise D, Chamoun GM, Rawls AZ, Demesa A, Turner T, Zheng B, Alexander BT, LaMarca B.   +9 more
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Absolute quantification of tumor necrosis factor-alpha by isotope dilution mass spectrometry. [PDF]

Front Chem
Bao C, Wang J, Xia W, Yang K, Shi X, Yang X, Li H, Wang Y, Zhang Y.   +8 more
europepmc   +1 more source

Selenium Nanoparticles Selectively Target KRAS G13D to Inhibit Colorectal Cancer

Advanced Science, EarlyView.
The mechanisms of SeNPs therapy in cancer treatment, encompass three parallel actions: (1) seleno‐amino acids, key metabolites, upregulate GPX2 expression, thereby inhibiting tumor metastasis via the GPX2‐HIF1α‐VEGF signaling pathway; (2) selenite (SeO32−), an inorganic metabolite, forms hydrogen bonds with amino acid residues 13–17 of the KRAS G13D ...
Xiaoting Liu, Chong Wu, Shiyao Song, Li Ma, Shaoqing Huang, Yuting He, Qinghai Li, Yanzhou Chang, Dan Jiang, Yong Mei, Junchao Cai, Zhenshuang Du, Tianfeng Chen, Weiling He   +13 more
wiley   +1 more source