Results 161 to 170 of about 314,005 (303)

Anti-tumor necrosis factor-alpha-induced psoriasis.

open access: yes, 2006
We describe a patient with rheumatoid arthritis who developed psoriasis during treatment with etanercept; psoriatic lesions resolved completely after the drug was discontinued. but returned on rechallenge.
Birlik, Merih   +5 more
core  

Management of Clinical Cardiac Sarcoidosis Isolated to the Heart With Tumor Necrosis Factor-Alpha Inhibitors. [PDF]

open access: yesJACC Case Rep
Malhi JK   +6 more
europepmc   +1 more source

Optimized Ex Vivo Human Liver Slice Culture Maintains Extended Viability and Function for Hepatotoxicity Testing

open access: yesAdvanced Science, EarlyView.
An optimized ex vivo human liver slice culture system preserves tissue architecture, hepatocyte function, and immune‐stromal complexity for at least five days. By refining slice thickness, oxygenation, air‐liquid interface, and extracellular matrix support, the platform enables human‐relevant hepatotoxicity testing and mechanistic studies, offering a ...
Huiche Feng   +17 more
wiley   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan   +10 more
wiley   +1 more source

Mechanisms of tumor necrosis factor-alpha inhibition of cAMP-induced Cyp17 gene expression in Leydig cells.

open access: yes, 1997
Mechanisms of tumor necrosis factor-alpha inhibition of cAMP-induced Cyp17 gene expression in Leydig ...
Xiangquan. Li (7973558)
core  

Tyrosinase Driven‐Intracellular Polymerization of a Porphyrin Derivative Induced Immunogenic Death of Melanoma Cells and Strengthened Photodynamic Therapy

open access: yesAdvanced Science, EarlyView.
This study uses tyrosinase, which is highly expressed in melanoma, to drive porphyrins to polymerize and self‐assemble within tumor cells to form retented microstructures. This process induces immunogenic death and activates immune responses (M1 macrophages, dendritic cells, CD8+T cells), turning “cold” tumors into “hot” tumors.
Mian Tang   +9 more
wiley   +1 more source

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang   +12 more
wiley   +1 more source

Differential effects of splice variants of human IG20 on tumor necrosis factor-alpha-induced apoptosis.

open access: yes, 2002
Differential effects of splice variants of human IG20 on tumor necrosis factor-alpha-induced ...
Adeeb Mohammad. Al-Zoubi (7966496)
core  

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