Results 201 to 210 of about 506,829 (351)

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Assessing the Significance of Interleukin-6, Interleukin-10, and Tumor Necrosis Factor-Alpha in Peri-Implantitis Development: A Biomarker Study. [PDF]

Cureus
Bhukal S, Malik R, Begum R, Adapala K, Killamsetty M, Arora P, Gupta S.   +6 more
europepmc   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Tumor Necrosis Factor-Alpha and Its Association With Breast Cancer: A Systematic Review. [PDF]

World J Oncol
Qodir N, Pramudhito D, Legiran, Hafy Z, Iman MB, Syafira F, Afladhanti PM, Daenasa RS, Indra B.   +8 more
europepmc   +1 more source

ACUTE EXERCISE SUPPRESSION OF TUMOR NECROSIS FACTOR-α EXPRESSION IN RAT LIVER

, 2002
Hiromi Matsuzaki, Hiromi Yano
openalex   +2 more sources

Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats.

Circulation, 1998
B. Bozkurt, S. Kribbs, F. Clubb, L. Michael, V. Didenko, P. Hornsby, Y. Seta, H. Oral, F. Spinale, D. Mann   +9 more
semanticscholar   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Therapeutic Potential of 7,8-Dimethoxycoumarin in Tumor Necrosis Factor-Alpha-Induced Trigeminal Neuralgia in a Rat Model. [PDF]

Curr Issues Mol Biol
Paramakrishnan N, Raadhika K, Elayaperumal S, Sivamani Y, Paramaswaran Y, Siang LJ, Venkata Rathina Kumar T, Lim KG, Ramesh M, Muthuraman A.   +9 more
europepmc   +1 more source

Tumor Necrosis Factor-Alpha antagonist improves functional recovery following olfactory system injury by suppressing local inflammation

, 2016
AL Salihi Mohammed, Masayoshi Kobayashi, Kengo Tamari, Tomotaka Miyamura, Kazuhiko Takeuchi   +4 more
openalex   +1 more source

Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.

Arthritis & Rheumatism, 1993
M. Elliott, R. Maini, M. Feldmann, A. Long-Fox, P. Charles, P. Katsikis, F. Brennan, J. Walker, H. Bijl, J. Ghrayeb, J. Woody   +10 more
semanticscholar   +1 more source