Results 211 to 220 of about 668,207 (351)

Tri‐Layered Bioactive Cutaneous Scaffold with Integrated Bioactive Metal Organic Frameworks to Promote Full‐Thickness Infected Diabetic Wound Healing: Multifaceted Therapeutic Strategies

Advanced Healthcare Materials, EarlyView.
The limitations of existing clinical treatments highlight the need for a more comprehensive strategy for addressing infected diabetic wounds. A tri‐layered scaffold is developed to deliver therapeutics loaded in CuBDC and ZIF‐8 MOFs that are tailored to the requirements of deep‐infected diabetic wounds.
Ayse Gunyakti Mujtaba, Ayşe Karakeçili, Berna Topuz, Barış Batur, Okan Onar, Mehmet Eray Elçiğir, Çağdaş Oto, Alireza Hanifehnezhad, Kaan Orhan   +8 more
wiley   +1 more source

The effects of tumor necrosis factor-alpha on early human hematopoietic progenitor cells treated with 4-hydroperoxycyclophosphamide [PDF]

, 1990
J Moreb, JR Zucali, S Rueth
openalex   +1 more source

Biomimetic Scaffolds Enhance iPSC Astrocyte Progenitor Angiogenic, Immunomodulatory, and Neurotrophic Capacity in a Stiffness and Matrix‐Dependent Manner for Spinal Cord Repair Applications

Advanced Healthcare Materials, EarlyView.
Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor, Ian Woods, Sarah F. McComish, Sean Kerr, Matthew McGrath, Juan Carlos Palomeque Chávez, Jack Maughan, Tara McGuire, Maeve A. Caldwell, Adrian Dervan, Fergal J. O'Brien   +10 more
wiley   +1 more source

Serum levels of tumor necrosis factor alpha in patients treated with granulocyte-macrophage colony-stimulating factor [letter; comment] [PDF]

, 1990
B Stehle, C Weiss, AD Ho, W Hunstein
openalex   +1 more source

β‐1,3 Glucan Microparticles & Nanoparticles: Fabrication Methods & Applications in Immunomodulation & Targeted Drug Delivery

Advanced Healthcare Materials, EarlyView.
Beta‐glucans have gained significant attention as an immunomodulatory biomaterial with cell‐targeting capabilities. This review comprehensively outlines the design and fabrication methods for producing beta‐glucan particles at both the micro and nanoscale and their applications in immune cell targeting, immunomodulation, and drug delivery ...
Nate Dowdall, Todd Hoare
wiley   +1 more source

Tumor necrosis factor alpha as a marker of systemic and local inflammation in “healthy” smokers

International Journal of General Medicine, 2009
Juan M Diez-Pina1, María J Fernandez-Aceñero3, María J Llorente-Alonso2, Salvador Diaz-Lobato4, Sagrario Mayoralas1, Asuncion Florez11Department of Pneumology; 2Department of Biochemistry, Hospital de Móstoles,
Juan M Diez-Pina, María J Fernandez-Aceñero, María J Llorente-Alonso, Salvador Diaz-Lobato, Sagrario Mayoralas, Asuncion Florez   +5 more
doaj  

Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation [see comments] [PDF]

, 1990
E Holler, HJ Kolb, A Moller, J Kempeni, S Liesenfeld, H Pechumer, W Lehmacher, G Ruckdeschel, B Gleixner, C Riedner   +9 more
openalex   +1 more source

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

Advanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen, Yingjie Fan, Tomas Germanas, Langston Tillman, Jinhong Li, Abigail L. Blenko, Ralph R. Weichselbaum, Wenbin Lin   +7 more
wiley   +1 more source

The production of tumor necrosis factor-.ALPHA. by rat basophilic leukemia cells with triggering IgE receptor.

, 1988
Isao Ohno, Yasuo Tanno, Kohei Yamauchi, Shiroh IDA, Tamotsu Takishima   +4 more
openalex   +2 more sources

Nanoplastics: Immune Impact, Detection, and Internalization after Human Blood Exposure by Single‐Cell Mass Cytometry

Advanced Materials, Volume 37, Issue 12, March 26, 2025.
The study investigates the effects of nanoplastics on human immune cells using palladium‐doped polystyrene nanoplastics and mass cytometry. It reveals that nanoplastics accumulate in various immune cell subpopulations, reducing cell viability and impairing function. In vivo experiments in mice confirm their accumulation in several immune cells.
Laura Fusco, Arianna Gazzi, Linda Giro, Roman B. Schefer, Sènan Mickael D'Almeida, Roberta Cagliani, Martina Zoccheddu, Recep Uyar, Ömur Besbinar, Doğantan Çelik, Acelya Yilmazer, Denise M. Mitrano, Marco Orecchioni, Lucia Gemma Delogu   +13 more
wiley   +1 more source