Results 221 to 230 of about 693,338 (390)

Evidence that Tristetraprolin Binds to AU-Rich Elements and Promotes the Deadenylation and Destabilization of Tumor Necrosis Factor Alpha mRNA

Molecular and Cellular Biology, 1999
W. Lai, E. Carballo, Julie R. Strum, E. Kennington, R. Phillips, P. Blackshear   +5 more
semanticscholar   +1 more source

Enhancing the Effectiveness of Chemotherapy in Osteosarcoma by Targeting Tumour‐Associated Macrophages (TAMs) through STING Activation

Advanced Therapeutics, EarlyView.
Osteosarcoma isa highly aggressive bone cancer with an immunosuppressive tumor microenvironment that limits immunotherapy. This study explores STING pathway activation to reprogram tumor‐associated macrophages into a tumoricidal M1‐like phenotype and enhance doxorubicin efficacy. Results show that doxorubicin alone failed to activate the STING pathway,
Jordan C. O'Donoghue, Amanda Guitián‐Caamaño, Maeve Boyce, Fiona E. Freeman   +3 more
wiley   +1 more source

Sex based relative expression of estrogen receptors and tumor necrosis factor-alpha in liver affects hepatitis C virus viral pathogenesis. [PDF]

World J Gastroenterol
Groover S, Addison S, Nicks S, Mwangi M, Brooks A, Kaul A, Kaul R.   +6 more
europepmc   +1 more source

Gene sequence of feline tumor necrosis factor alpha

Nucleic Acids Research, 1990
Clarence A. Rawlings, Bradford W. Coffee, R A McGraw, Cynthia M. Otto, Roman T. Drews   +4 more
openaire   +4 more sources

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

Advanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source

Three-year outcomes of tumor necrosis factor alpha inhibitor therapy in rheumatoid arthritis patients with elevated liver enzymes. [PDF]

World J Hepatol
Duggal S, Kattamuri L, Sairam S.
europepmc   +1 more source

Tumor necrosis factor-alpha enhances platelet activation via cathepsin G released from neutrophils. [PDF]

, 1991
Patricia Renesto, Michel Chignard
openalex   +1 more source

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

Proceedings of the National Academy of Sciences of the United States of America, 1993
C. Tripp, S. Wolf, E. Unanue
semanticscholar   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

Kv11.1-dependent senescence activates a lethal immune response via tumor necrosis factor alpha. [PDF]

Neoplasia
Saatloo MV, Delisi D, Eskandari N, Krieg C, Gentile S.   +4 more
europepmc   +1 more source