Results 221 to 230 of about 501,207 (351)

Interferon‐Driven Biomarkers and Synergistic Therapy for PRMT5 Inhibition in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
Triple‐negative breast cancer exhibits variable sensitivity to PRMT5 inhibition. Basal interferon signaling is identified as a key biomarker of response. PARP inhibition with olaparib induces IFN signaling, sensitizing resistant TNBC cells to PRMT5 inhibitors.
Ziwen Zhang, Sheyu Zhang, Lu Guo, Yichun Pan, Juan Huang, Yishuai Ji, Jiaqi Tao, Yong Wei, Xiaojia Wang, Qin Wu   +9 more
wiley   +1 more source

Increased levels of tumor necrosis factor-alpha in rat with traumatic brain injury after NeuroAid (MLC 901) administration. [PDF]

Surg Neurol Int
Rohadi, Priyanto B, Islam AA, Hatta M, Bukhari A, Rozikin, Eka Putra IWGA, Abdurrosid LM, Prihastomo KT.   +8 more
europepmc   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Serum tumor necrosis factor alpha increased during remission with Etanercept

Pediatric Rheumatology Online Journal, 2011
Miu Nicolae, Bolba Claudia, Samasca Gabriel, Spirchez Mihaela   +3 more
doaj   +1 more source

Sex based relative expression of estrogen receptors and tumor necrosis factor-alpha in liver affects hepatitis C virus viral pathogenesis. [PDF]

World J Gastroenterol
Groover S, Addison S, Nicks S, Mwangi M, Brooks A, Kaul A, Kaul R.   +6 more
europepmc   +1 more source

Effects of RP 55778, a tumor necrosis factor alpha synthesis inhibitor, on antiviral activity of dideoxynucleosides [PDF]

, 1997
Pascal Clayette, N Dereuddre-Bosquet, Marc Martín, Philippe Frétier, Dominique Dormont   +4 more
openalex   +1 more source

Treatment of rheumatoid arthritis with chimeric monoclonal antibodies to tumor necrosis factor alpha.

Arthritis & Rheumatism, 1993
M. Elliott, R. Maini, M. Feldmann, A. Long-Fox, P. Charles, P. Katsikis, F. Brennan, J. Walker, H. Bijl, J. Ghrayeb, J. Woody   +10 more
semanticscholar   +1 more source

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

Advanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu, Yun Teng, Yinan Huang, Jingyao Mu, Lucy Teng, Hongjia Qian, Qiming Huang, Minmin Liu, Yi Zou, Lifeng Zhang, Michael L Merchant, Xiang Zhang, Jun Yan, Huang‐Ge Zhang   +13 more
wiley   +1 more source

Three-year outcomes of tumor necrosis factor alpha inhibitor therapy in rheumatoid arthritis patients with elevated liver enzymes. [PDF]

World J Hepatol
Duggal S, Kattamuri L, Sairam S.
europepmc   +1 more source

Tumor necrosis factor-alpha expression in ischemic neurons.

Stroke, 1994
T. Liu, R. Clark, P. Mcdonnell, P. Young, R. F. White, F. Barone, G. Feuerstein   +6 more
semanticscholar   +1 more source