Results 231 to 240 of about 501,207 (351)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Central nervous system effects of tumor necrosis factor alpha blockade

Journal of Translational Medicine, 2011
Schett Georg
doaj   +1 more source

FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine

Advanced Science, EarlyView.
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang, Yinghui Xu, Xianpeng Wu, Mo Li, Changchen Xiao, Zaiyang Fu, Yongjian Chen, Qingju Li, Yating Ruan, Jing Zhao, Zhiwei Zhong, Jinghai Chen, Wei Zhu, Jinliang Nan, Cheng Ni, Xinyang Hu   +15 more
wiley   +1 more source

Tumor Necrosis Factor-Alpha Inhibitor-Induced Sarcoid-Like Reaction in a Patient With Juvenile Idiopathic Arthritis: A Case Report. [PDF]

Cureus
Aung T, Prasanpanich M, Kaplan A, Eblen K, Fishbein GA.   +4 more
europepmc   +1 more source

Adiponectin expression from human adipose tissue: relation to obesity, insulin resistance, and tumor necrosis factor-alpha expression.

Diabetes, 2003
P. Kern, G. D. Di Gregorio, T. Lu, N. Rassouli, G. Ranganathan   +4 more
semanticscholar   +1 more source

Gene sequence of porcine tumor necrosis factor alpha

Nucleic Acids Research, 1990
R T, Drews, B W, Coffee, A K, Prestwood, R A, McGraw   +3 more
openaire   +3 more sources

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Interferon Gamma and Tumor Necrosis Factor Alpha Are Inflammatory Biomarkers for Major Adverse Cardiovascular Events in Patients with Peripheral Artery Disease. [PDF]

Biomedicines
Li B, Lindner E, Abuhalimeh R, Shaikh F, Younes H, Abuhalimeh B, Zamzam A, Abdin R, Qadura M.   +8 more
europepmc   +1 more source

Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis

Molecular and Cellular Biology, 1997
S. Yoshida, M. Ono, T. Shono, H. Izumi, T. Ishibashi, Hideo Suzuki, M. Kuwano   +6 more
semanticscholar   +1 more source

What is Tumor Necrosis Factor Alpha ?

Turkiye Klinikleri Journal of Internal Medicine, 2018
openaire   +1 more source