Results 231 to 240 of about 493,933 (351)

Lifespan‐Regulated CAR‐Macrophages from Myeloid Progenitors for Enhanced Colorectal Cancer Therapy

Advanced Science, EarlyView.
Using a tamoxifen‐inducible Hoxb8 system, proliferative bone marrow progenitors can be generated, which are subsequently engineered with an anti‐CEA CAR construct containing a suicide gene (iCas9) and differentiated into CAR‐macrophages. This method facilitates scale up the production of CAR‐macrophages.
Chuancheng Gao, Fangling Hong, Yao Dong, Yong Fu, Yunong Ma, Xuedi Sun, Junfeng Zhang, Jiangning Chen, Zhen Huang   +8 more
wiley   +1 more source

Kv11.1-dependent senescence activates a lethal immune response via tumor necrosis factor alpha. [PDF]

Neoplasia
Saatloo MV, Delisi D, Eskandari N, Krieg C, Gentile S.   +4 more
europepmc   +1 more source

Autocrine tumor necrosis factor (TNF) and lymphotoxin (LT) alpha differentially modulate cellular sensitivity to TNF/LT-alpha cytotoxicity in L929 cells. [PDF]

, 1998
Akashi, Androlewicz, Black, Browning, Browning, Browning, Chaturvedi, Chiacchia, Crowe, De Togni, Decoster, Engelmann, English, Espevik, Espevik, Estrov, Fiers, Fransen, Hass, Huylebroeck, Koni, Kriegler, Krönke, Lewis, Lucas, Mackay, Mantovani, Matthews, Mellow, Moss, Müller, Nedospasov, Olsen, Paul, Southern, Spies, Steer, Sung, Tada, Tang, Tartaglia, Tartaglia, Tartaglia, Tartaglia, Vandenabeele, Vanhaesebroeck, Vanhaesebroeck, Vercammen, Vilček   +48 more
core   +2 more sources

Differential augmentation by recombinant human tumor necrosis factor-alpha of neutrophil responses to particulate zymosan and glucan. [PDF]

, 1990
Robert Steadman, Meryl M. Petersen, Nicholas Topley, David W. Williams, Nick C. Matthews, Bernd W. Spur, J. D. Williams   +6 more
openalex   +1 more source

RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53R249S Mutation and is a Potential Therapeutic Target

Advanced Science, EarlyView.
Genome‐wide CRISPR/Cas9 based screening identified RELA as a key tumor suppressor in TP53R249S‐mutant HCC. Its loss promotes tumorigenesis and metastasis via DVL1‐mediated Wnt/β‐catenin activation, while its agonist betulinic acid suppresses tumor progression.
Zhiping Wu, Zhe Wang, Diwei Zheng, Yongfang Zheng, Zhiwu Jiang, Jiang Lv, Yueqin Zhu, Heng Jia, Ziyuan Duan, Tingjie Yuan, Qiting Wu, Youguo Long, Shouheng Lin, Yao Yao, Georgia Carson, Jean P. Thiery, Kwan Man, Peng Li   +17 more
wiley   +1 more source

Tumor Necrosis Factor-Alpha Inhibitor-Induced Sarcoid-Like Reaction in a Patient With Juvenile Idiopathic Arthritis: A Case Report. [PDF]

Cureus
Aung T, Prasanpanich M, Kaplan A, Eblen K, Fishbein GA.   +4 more
europepmc   +1 more source

Differential inhibition of lipopolysaccharide-induced phenomena by anti-tumor necrosis factor alpha antibody [PDF]

, 1990
Stefanie N. Vogel, Edward A. Havell
openalex   +1 more source

Ultrathin Multi‐Doped Molybdenum Oxide Nanodots as a Tunable Selective Biocatalyst

Advanced Science, EarlyView.
This paper presents an advanced multi‐doped molybdenum oxide nanodots with tunable ammonium and proton doping, exhibiting strong ROS generation. The material demonstrates ultrafast and complete dye degradation and unique selective toxicity toward cancer cells, highlighting its promising potential for cancer therapy applications.
Bao Yue Zhang, Farjana Haque, Shwathy Ramesan, Sanjida Afrin, Muhammad Waqas Khan, Haibo Ding, Xin Zhou, Qijie Ma, Jiaru Zhang, Rui Ou, Md Mohiuddin, Enamul Haque, Yichao Wang, Azmira Jannat, Yumin Li, Robi S. Datta, Kate Fox, Guolang Li, Hujun Jia, Jian Zhen Ou   +19 more
wiley   +1 more source

Interferon Gamma and Tumor Necrosis Factor Alpha Are Inflammatory Biomarkers for Major Adverse Cardiovascular Events in Patients with Peripheral Artery Disease. [PDF]

Biomedicines
Li B, Lindner E, Abuhalimeh R, Shaikh F, Younes H, Abuhalimeh B, Zamzam A, Abdin R, Qadura M.   +8 more
europepmc   +1 more source

Effects of recombinant human interleukin-6 alone and in combination with recombinant interleukin-1 alpha and tumor necrosis factor alpha on antibacterial resistance in mice [PDF]

, 1992
Charles J. Czuprynski, Mary Haak‐Frendscho, N Maroushek, J F Brown   +3 more
openalex   +1 more source