Results 191 to 200 of about 725,440 (353)

PG490 (Triptolide) Cooperates with Tumor Necrosis Factor-α to Induce Apoptosis in Tumor Cells [PDF]

open access: hybrid, 1999
Kye Young Lee   +4 more
openalex   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang   +12 more
wiley   +1 more source

TUMOR NECROSIS FACTOR AND SOLUBLE TUMOR NECROSIS FACTOR RECEPTOR LEVELS IN ASCITES

open access: yesThe Turkish Journal of Gastroenterology, 1994
U. YILMAZ   +5 more
doaj  

DETECTION OF PLASMA TUMOR-NECROSIS-FACTOR, INTERLEUKIN-6, AND INTERLEUKIN-8 DURING THE JARISCH-HERXHEIMER REACTION OF RELAPSING FEVER

open access: yes, 1992
S L Kunkel   +11 more
core   +1 more source

No impact of tumor necrosis-factor antagonists on the joint manifestations of sarcoidosis

open access: yes, 2013
Christopher Banse,1 Aurélia Bisson-Vaivre,1 Marie Kozyreff-Meurice,1 Olivier Vittecoq,1 Vincent Goëb2 1Rheumatology Department, Rouen University Hospital, Rouen, France; 2Rheumatology Department, Amiens University Hospital, Amiens, France ...
Banse C   +4 more
core  

PRMT1‐Mediated LDHA Methylation Drives STAT3 Lactylation to Orchestrate Intestinal Inflammation and Tumorigenesis

open access: yesAdvanced Science, EarlyView.
This study identifies an immunometabolic axis wherein SAM‐driven PRMT1 methylates LDHA, enhancing its activity. The resultant lactate induces STAT3 K709 lactylation, which stabilizes an active conformation to promote STAT3 phosphorylation and IL‐10 expression.
Hui Wang   +12 more
wiley   +1 more source

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