Results 91 to 100 of about 729,544 (396)

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Measurement of tumor necrosis factor-α, leukotriene B4, and interleukin 8 in the exhaled breath condensate in patients with acute exacerbations of chronic obstructive pulmonary disease

International Journal of COPD, 2008
Fanny WS Ko1, Ting-Fan Leung2, Gary WK Wong2, Jenny Ngai1, Kin W To1, Susanna Ng1, David SC Hui11Department of Medicine and Therapeutics; 2Department of Pediatrics, The Chinese University of Hong Kong, Hong KongBackground: Assessment of airway ...
Fanny WS Ko, Ting-Fan Leung, Gary WK Wong, Jenny Ngai, Kin W To, et al   +5 more
doaj  

Evaluation of C-reactive protein, procalcitonin, tumor necrosis factor alpha, interleukin-6, and interleukin-8 as diagnostic parameters in sepsis-related fatalities [PDF]

, 2018
The aims of this study were to investigate the usefulness of serum C-reactive protein, procalcitonin, tumor necrosis factor alpha, interleukin-6, and interleukin-8 as postmortem markers of sepsis and to compare C-reactive protein and procalcitonin values
Mangin, Patrice, Palmiere, Cristian, Roux-Lombard, Pascale, Schneiter, Deborah, Schrag, Bettina, Vaucher, Paul   +5 more
core  

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source

Incidence of Toxoplasmosis in Psoriasis Patients and Possible Correlation with Tumor Necrosis Factor-α

مجلة بغداد للعلوم, 2020
Toxoplasma gondii is an opportunistic parasite in immune-compromised persons. The prevalence of toxoplasmosis in psoriasis patients is investigated. In addition, the treatment effect on psoriasis patients infected with toxoplasmosis through evaluating ...
Entsar J. Saheb, Yasser A.H Al-Issa, Israa Salim Mussa, Khawla H. Zghair   +3 more
doaj   +1 more source

Value of infliximab (Remicade) in patients with low-risk myelodysplastic syndrome. Final results of a randomized phase II trial (EORTC trial 06023) of the EORTC Leukemia Group [PDF]

, 2011
peer reviewedTumor-necrosis factor alpha activity has been correlated to ineffective erythropoiesis in lower risk myelodysplastic syndromes. Infliximab (Remicade) is an anti-tumor-necrosis factor alpha chimeric antibody that is used in the treatment of ...
Amadori, Sergio, Baron, Frédéric, De Witte, Theo, Delforge, Michel, Denzlinger, Claudio, Indrak, Karel, Muus, Petra, Ossenkoppele, Geert, Selleslag, Dominik, Suciu, Stefan, Thyss, Antoine, Zwierzina, Heinz   +11 more
core   +2 more sources

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Serum tumor necrosis factor alpha and C-reactive protein increase in breast cancer patients [PDF]

Al Ameen Journal of Medical Sciences, 2018
Background: Breast cancer is now the second most commonly cancer diagnosed in women and remains the leading cause of cancer death among females in less developed countries.
Johnkennedy Nnodim, Orji Somtochukwu M, Ihionu Chukwudozie A   +2 more
doaj  

Cytokines and chemokines as regulators of skeletal muscle inflammation: presenting the case of Duchenne muscular dystrophy [PDF]

, 2013
Duchenne muscular dystrophy is a severe inherited muscle disease that affects 1 in 3500 boys worldwide. Infiltration of skeletal muscle by inflammatory cells is an important facet of disease pathophysiology and is strongly associated with disease ...
De Bleecker, Jan, De Paepe, Boel
core   +3 more sources

Tumor Necrosis Factor Alpha In Preeclampsia

, 2013
Pre-eclampsia is one of the most frequent complications of pregnancy, however, little is known about its aetiology. Insufficient adaptation of the decidual and intramyometrial portions of the spiral arterioles in preeclampsia results in reduced utero-placental blood flow, leading to local placental hypoxia.
Fozia A Patigaroo, Siddiqui, Anwar H, Gulat, Rajiv, ZehraMohsin   +3 more
openaire   +1 more source