Results 211 to 220 of about 666,626 (377)

The Mitogenic Response to Tumor Necrosis Factor Alpha Requires c-Jun/AP-1 [PDF]

, 1993
Marion A. Brach, Hans‐Jürgen Gruss, C Sott, F. Herrmann   +3 more
openalex   +1 more source

Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications

Advanced Science, EarlyView.
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang, Xiaofan Zhu, Zhenzhou Huang, Kaidi Ren, Jie Ran, Yang Yang   +5 more
wiley   +1 more source

Tumor Necrosis Factor-Alpha Inhibitor Use and Malignancy Risk: A Systematic Review and Patient Level Meta-Analysis. [PDF]

Cancers (Basel)
Driscoll CB, Rich JM, Isaacson D, Nicolas J, Jiang Y, Mi X, Yang C, Kocsuta V, Goh R, Patel N, Li E, Siddiqui MR, Meyers T, Witte JS, Kachuri L, Zhang H, Beestrum M, Silberman P, Schaeffer EM, Kundu SD.   +19 more
europepmc   +1 more source

Serum tumor necrosis factor alpha concentrations and clinical abnormalities in colostrum-fed and colostrum-deprived neonatal foals given endotoxin [PDF]

, 1993
Gary K. Allen, Eleanor M. Green, Julie A. Robinson, Harold E. Garner, Wayne Eugene Loch, Donald M. Walsh   +5 more
openalex   +1 more source

Lactylation‐Driven NUPR1 Promotes Immunosuppression of Tumor‐Infiltrating Macrophages in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Cai et al. report that tumor‐derived lactate induces NUPR1 expression via H3K18 lactylation, which can promote the pro‐tumor M2 macrophage polarization through ERK and JNK signaling pathways. Treatment with NUPR1 selective inhibitor sensitizes synergizes with anti‐PD‐1 therapy in murine preclinical models.
Jialiang Cai, Peiling Zhang, Yufan Cai, Guiqi Zhu, Shiping Chen, Lina Song, Junxian Du, Biao Wang, Weixing Dai, Jian Zhou, Jia Fan, Yiyi Yu, Zhi Dai   +12 more
wiley   +1 more source

Serum Vitamin D Level Correlates Significantly With Leptin and Tumor Necrosis Factor-Alpha in Overweight Postmenopausal Women With Hypertension. [PDF]

J Clin Med Res
Qahwaji DM, Serafi AS, Alaamri S, Hussain Z, Bafail MA, Gondi CS, Demirkhanyan L, Waraich RS, Sohail S.   +8 more
europepmc   +1 more source

(S)-Form of .ALPHA.-Methyl-N(.ALPHA.)-phthalimidoglutarimide, but Not Its (R)-Form, Enhanced Phorbol Ester-Induced Tumor Necrosis Factor-.ALPHA. Production by Human Leukemia Cell HL-60: Implication of Optical Resolution of Thalidomidal Effects.

, 1994
Koji Nishimura, Yasunari Hashimoto Yasunari Hashimoto, Shintaro Iwasaki   +2 more
openalex   +2 more sources

Differential inhibition of lipopolysaccharide-induced phenomena by anti-tumor necrosis factor alpha antibody [PDF]

, 1990
Stefanie N. Vogel, Edward A. Havell
openalex   +1 more source

Verteporfin‐Mediated In Situ Nanovaccine Based on Local Conventional‐Dose Hypofractionated Radiotherapy Enhances Antitumor and Immunomodulatory Effect

Advanced Science, EarlyView.
Here gelatinase‐responsive methoxypolyethyleneglycol–PVGLIG–polycaprolactone (mPEG–PVGLIG–PCL) nanoparticles’ loading verteporfin (N@VP) is developed, enhancing radiotherapy via X‐ray‐triggered singlet oxygen generation. Combined with 2 Gy (gray, a radiation dose unit) irradiation, N@VP achieves antitumor efficacy comparable to 8 Gy, and also promotes ...
Zhifan Zhang, Lin Li, Yuchen Ge, Anni Chen, Shanchao Diao, Yueling Yang, Qianyue Chen, Yingling Zhou, Jie Shao, Fanyan Meng, Lixia Yu, Manman Tian, Xiaoping Qian, Zhaoyu Lin, Chen Xie, Baorui Liu, Rutian Li   +16 more
wiley   +1 more source

Incidence and Risk Factors for Invasive Fungal Infections in Patients Initiating Tumor Necrosis Factor-Alpha Inhibitors for Inflammatory Bowel Disease and Rheumatoid Arthritis. [PDF]

Clin Infect Dis
Hennessee I, Benedict K, Bahr NC, Lipner SR, Gold JAW.   +4 more
europepmc   +1 more source